Please see the JBrowse view of Dmel\c-cup for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.47
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\c-cup using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
c-cup transcripts are detected at low levels in primary spermatocytes and are barely detected in early elongation spermatids. Robust signals are detected in more elongated spermatids at the distal ends. Transcripts localize in shallow cup-like shapes at the ends of spermatids bundles (called a cup pattern).
JBrowse - Visual display of RNA-Seq signals
View Dmel\c-cup in JBrowse2-3
2-3.2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
c-cup transcripts accumulate in cup-shaped structures also at the distal tips of elongating spermatids.
Source for identity of: c-cup CG15623
The gene is named "calcutta-cup", based on the "cup"-like pattern of expression of the transcript in spermatid bundles; the mRNA localises in shallow cup-like shapes at the end of the spermatid bundles.