ori
Please see the JBrowse view of Dmel\uri for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.52
There is only one protein coding transcript and one polypeptide associated with this gene
Interacts with serine/threonine-protein phosphatases flw/PP1beta9C and Pp1-87B with higher affinity for Pp1-87B.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\uri using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Comment: uniform
Comment: uniform
Comment: uniform
Comment: early primary spermatocytes
uri transcript is uniformly distributed in embryos, and in larval imaginal discs and brains. In adult males, uri transcript is localized to the apical tip of the testis, where it is expressed from mitotically proliferating spermatogonia through early primary spermatocytes. Expression decreases as spermatocytes mature, and is undetectable in post-meiotic stages.
Comment: Adult expression in gonads only
uri protein is expressed at all stages of development, but is most abundant in early embryos, pupal stages, and in adult gonads. In interphase cells, uri protein is predominantly cytoplasmic with a punctate distribution. uri protein localizes to transcriptionally active regions of polytene chromosomes.
JBrowse - Visual display of RNA-Seq signals
View Dmel\uri in JBrowse2-107
2-111.0
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
FlyBase curator comment: Correspondence with author Shi revealed that 'dURI' = 'CG11416'.
Source for identity of: ori CG11416
Source for identity of: uri ori