FlyBase Gene Report: Dmel\Haspin

General Information

Symbol

Dmel\Haspin

Species

D. melanogaster

Name

Haspin

Annotation Symbol

CG40080

Feature Type

protein_coding_gene

FlyBase ID

FBgn0046706

Gene Model Status

Current

Stock Availability

6 publicly available

Gene Summary

Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-4' (H3T3ph) during mitosis and interphase (PubMed:32750047). Function is essential for chromosome organization during mitosis and genome organization in interphase cells, thus playing a functional role in gene regulation (PubMed:32750047). During mitosis, may act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle (By similarity). During interphase, associates with the cohesion complex and mediates pds5 binding to chromatin to ensure correct sister chromatid cohesion, chromatin organization, and also functions with Pds5-cohesin to modify Polycomb-dependent homeotic transformations (PubMed:32750047). Function during interphase is required for insulator activity, nuclear compaction, heterochromatin-induced position-effect variegation and PcG-mediated pairing-sensitive silencing (PubMed:32750047). (UniProt, P83103)

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All Summaries

Alliance
Auto summary
Gene Group
UniProtKB
Interactive Fly

Key Links

Genomic Location

Cytogenetic map

41A1-41A1

Sequence location

2R:4,014,111..4,049,342 [+]

Recombination map

2-55

RefSeq locus

NT_033778 REGION:4014111..4049342

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

NCBI

UCSC

Ensembl

Function

Gene Ontology (GO) Annotations (15 terms)

Molecular Function (4 terms)

Terms Based on Experimental Evidence (2 terms)

CV Term

Evidence

References

enables histone H3T3 kinase activity

inferred from mutant phenotype

(Fresán et al., 2020)

enables protein binding

inferred from physical interaction with UniProtKB:A1Z8S6

(Fresán et al., 2020)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

enables ATP binding

inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR017441

(InterPro Project Members, 2004-)

inferred from sequence or structural similarity with UniProtKB:Q8TF76

(Gene Ontology Curators, 2002-)

enables histone H3T3 kinase activity

inferred from sequence or structural similarity with HGNC:19682

(Gene Ontology Curators, 2002-)

inferred from biological aspect of ancestor with PANTHER:PTN000784925

(GO Reference Genome Project, 2011-)

enables protein kinase activity

inferred from electronic annotation with InterPro:IPR000719

(InterPro Project Members, 2004-)

Biological Process (7 terms)

Terms Based on Experimental Evidence (4 terms)

CV Term

Evidence

References

involved_in positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric

inferred from mutant phenotype

(Fresán et al., 2020)

involved_in positive regulation of maintenance of sister chromatid cohesion

inferred from mutant phenotype

(Fresán et al., 2020)

involved_in positive regulation of protein localization to chromatin

inferred from mutant phenotype

(Fresán et al., 2020)

involved_in post-translational protein modification

inferred from mutant phenotype

(Fresán et al., 2020)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

involved_in intracellular signal transduction

inferred from biological aspect of ancestor with PANTHER:PTN000784925

(GO Reference Genome Project, 2011-)

inferred from sequence or structural similarity with UniProtKB:Q8TF76

(Gene Ontology Curators, 2002-)

involved_in mitotic cell cycle

inferred from biological aspect of ancestor with PANTHER:PTN000784925

(GO Reference Genome Project, 2011-)

involved_in protein phosphorylation

inferred from sequence or structural similarity with UniProtKB:Q8TF76

(Gene Ontology Curators, 2002-)

Cellular Component (4 terms)

Terms Based on Experimental Evidence (2 terms)

CV Term

Evidence

References

part_of chromatin

inferred from mutant phenotype

(Fresán et al., 2020)

located_in nuclear lamina

inferred from direct assay

(Fresán et al., 2020)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

is_active_in cytoplasm

inferred from biological aspect of ancestor with PANTHER:PTN000784925

(GO Reference Genome Project, 2011-)

is_active_in nucleus

inferred from biological aspect of ancestor with PANTHER:PTN000784925

(GO Reference Genome Project, 2011-)

located_in nucleus

inferred from sequence or structural similarity with UniProtKB:Q8TF76

(Gene Ontology Curators, 2002-)

Gene Group (FlyBase)

UNCLASSIFIED CONVENTIONAL PROTEIN KINASE DOMAIN KINASES

Protein Family (UniProt)

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Haspin subfamily. (P83103)

Protein Signatures (InterPro)

Summaries

Gene Group (FlyBase)

UNCLASSIFIED CONVENTIONAL PROTEIN KINASE DOMAIN KINASES -: This group comprises conventional protein kinase domain kinases that do not classify under other groups in FlyBase.

Protein Function (UniProtKB)

(UniProt, P83103)

Summary (Interactive Fly)

a kinase that associates with the cohesin complex in interphase - mediates Pds5 binding to chromatin - cooperates with Pds5-cohesin to modify Polycomb-dependent homeotic transformations - asymmetric inheritance of centromeric proteins upon stem cell division - regulation of stem cell fate in asymmetric cell division - phosphorylation at threonine 3 of H3 distinguishes pre-existing versus newly synthesized H3 distinguishing sister chromatids enriched with distinct pools of H3 in order to coordinate asymmetric segregation of "old" H3 into GSCs - tight regulation of H3T3 phosphorylation is required for male germline activity

Interactive Fly

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\Haspin for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry P83103)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.47

Sequence Ontology: Class of Gene

gene_with_edited_transcript

(Rodriguez et al., 2012)

nuclear_gene

protein_coding_gene

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

Haspin-RA

FBtr0113784

NM_001015349

1815

566

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

Haspin-PA

FBpp0112507

65.3

566

8.39

P83103

NP_001015349

EAA46104

Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Subunit Structure (UniProtKB)

Interacts with pds5 and vtd.

(UniProt, P83103)

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

P83103

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Haspin using the Feature Mapper tool.

External Data

Crossreferences

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

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Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 11 -- 12

amnioserosa

(Fisher et al., 2012)

embryonic stage 13 -- 16

amnioserosa

(Fisher et al., 2012)

embryonic/larval plasmatocyte

(Fisher et al., 2012)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

part_of chromatin

inferred from mutant phenotype

(Fresán et al., 2020)

located_in nuclear lamina

inferred from direct assay

(Fresán et al., 2020)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Haspin in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\Haspin

View exonic expression by tissue for Dmel\Haspin

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0046706

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

3355064/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0046706

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0046706

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0046706

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG40080

Flygut - An atlas of the Drosophila adult midgut

FBgn0046706

Images

FlyExpress - Embryonic expression images (BDGP data)

Show all FlyExpress processed images for Dmel\Haspin

Stages(s) 13-16

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 4 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 9 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Haspin

Transgenic constructs containing regulatory region of Haspin

Aberrations (Deficiencies and Duplications) ( 2 )

Inferred from experimentation ( 2 )

Gene disrupted in

Df(2R)34-2

(Coulthard et al., 2010)

Df(2R)247

(Coulthard et al., 2010)

Inferred from location ( 0 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

viable

Haspin¹²⁸

viable, with Scer\GAL4^{VP16.mat.αTub67C}

Haspin^GL00176

Sterility

Allele

female semi-fertile

Haspin¹²⁸

female semi-sterile, with Scer\GAL4^{VP16.nanos.UTR}, Scer\GAL4^VP16.otu, Scer\GAL4^nanos.PG

Haspin^GL00176

fertile

Haspin¹²⁸

fertile, with Scer\GAL4^{VP16.mat.αTub67C}

Haspin^GL00176

male semi-fertile

Haspin¹²⁸

Other Phenotypes

Allele

abnormal mitotic cell cycle | larval stage

Haspin¹²⁸

short lived

Haspin¹²⁸

suppressor of variegation | dominant

Haspin¹²⁸

Phenotype manifest in

Allele

embryonic/larval brain | larval stage

Haspin¹²⁸

embryonic/larval salivary gland | larval stage

embryonic/larval salivary gland | larval stage, with Scer\GAL4^nub.PU

Haspin^GL00176

embryonic/larval salivary gland | third instar larval stage

Haspin⁸⁶

nucleus | larval stage

nucleus | larval stage, with Scer\GAL4^nub.PU

Haspin^GL00176

nucleus | third instar larval stage

Haspin⁸⁶

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (4)

Hsap\HASPIN

9 of 14

Yes

Hsap\IRAK1

1 of 14

Hsap\IRAK2

1 of 14

Hsap\IRAK3

1 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (4)

Rnor\Haspin

10 of 14

Yes

Rnor\Irak1

1 of 14

Rnor\Irak2

1 of 14

Rnor\Irak3

1 of 14

Mus musculus (laboratory mouse) (4)

Mmus\Haspin

9 of 14

Yes

Mmus\Irak1

1 of 14

Mmus\Irak2

1 of 14

Mmus\Irak3

1 of 14

Xenopus tropicalis (Western clawed frog) (2)

Xtro\haspin

5 of 13

Yes

Xtro\fam189b

1 of 13

Yes

Danio rerio (Zebrafish) (3)

Drer\haspin

7 of 14

Yes

Drer\irak1

1 of 14

Drer\irak3

1 of 14

Caenorhabditis elegans (Nematode, roundworm) (21)

Cele\hasp-1

10 of 14

Yes

Cele\hasp-2

9 of 14

Yes

Cele\F59E12.15

4 of 14

Yes

Cele\VY10G11R.1

4 of 14

Yes

Cele\ZK177.2

4 of 14

Yes

Cele\C06E4.5

3 of 14

Yes

Cele\H12I13.1

3 of 14

Yes

Cele\Y48B6A.10

3 of 14

Yes

Cele\Y73B6A.1

3 of 14

Yes

Cele\C04G2.10

2 of 14

Yes

Cele\C26E6.1

2 of 14

Yes

Cele\C50H2.7

2 of 14

Yes

Cele\C55C3.8

2 of 14

Yes

Cele\Y32G9A.3

2 of 14

Yes

Cele\F12A10.6

1 of 14

Yes

Cele\F22H10.5

1 of 14

Yes

Cele\hil-8

1 of 14

Yes

Cele\K08B4.5

1 of 14

Yes

Cele\W02H3.3

1 of 14

Yes

Cele\W03F9.3

1 of 14

Yes

Cele\Y40A1A.1

1 of 14

Yes

Anopheles gambiae (African malaria mosquito) (2)

Agam\AgaP_AGAP011191

6 of 12

Yes

Agam\AgaP_AGAP010690

1 of 12

Arabidopsis thaliana (thale-cress) (1)

Atha\Haspin

10 of 13

Yes

Saccharomyces cerevisiae (Brewer's yeast) (2)

Scer\ALK2

5 of 13

Yes

Scer\ALK1

4 of 13

Yes

Schizosaccharomyces pombe (Fission yeast) (1)

Spom\hrk1

11 of 12

Yes

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:Haspin. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (1)

pll

2 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

HASPIN; histone H3 associated protein kinase

9 of 14

609240

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Show neighbor-neighbor interactions:

Off

Show/hide secondary interactors
(data from AllianceMine provided by esyN)

Select Layout:

Force Directed

Circle

Concentric

Legend:

Protein

RNA

Selected Interactor(s)

Other Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

Haspin - pds5

anti bait coimmunoprecipitation, anti tag western blot

(Fresán et al., 2020)

Haspin - vtd

anti bait coimmunoprecipitation, anti tag western blot

(Fresán et al., 2020)

Summary of Genetic Interactions

esyN Network Diagram

Show/hide secondary interactors
(data from AllianceMine provided by esyN)

esyN Network Key:

Suppression

Enhancement

Other Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Haspin|Pc

enhanceable

pds5

(Fresán et al., 2020)

Haspin|Pc

enhanceable

vtd

(Fresán et al., 2020)

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

enhanceable

Haspin

(Fresán et al., 2020)

suppressible

Haspin

(Fresán et al., 2020)

External Data

Subunit Structure (UniProtKB)

Interacts with pds5 and vtd.

(UniProt, P83103 )

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0046706

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

External Data

Linkouts

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

2-55

Cytogenetic map

41A1-41A1

Sequence location

2R:4,014,111..4,049,342 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

41A1-41A1

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

h45-h46

(determined by in situ hybridisation)

(Rossi et al., 2007)

Heterochromatic, cytological location not yet determined.

(Drosophila Heterochromatin Genome Project, 2004)

Experimentally Determined Recombination Data

Location

2-55

(FlyBase, 2016)

2-55.3

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (6)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

53099

y¹ w^*; Mi{MIC}Haspin^MI09386

76709

y¹ w^*; Mi{Trojan-GAL4.0}Haspin^{MI09386-TG4.0}

35276

y¹ sc^* v¹ sev²¹; P{TRiP.GL00176}attP2

57787

y¹ sc^* v¹ sev²¹; P{TRiP.HMC04981}attP40

VDRC

v330638

P{VSH330638}attP40

v342727

P{hsFLP}1, y1 w1118; P{HD_CFD01445}attP40/CyO-GFP

Genomic Clones (16)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (20)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

LD07633

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0046706

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0046706

Antibody Information

Laboratory Generated Antibodies

polyclonal

(Fresán et al., 2020)

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

New annotation (CG40080) in release 3 of the genome annotation.

(FlyBase Genome Annotators, 2002-2003)

Relationship to Other Genes

Source for database merge of

Source for merge of: Haspin CG40080

(FlyBase, 1996-)

Source for merge of: Haspin BcDNA:LD07633

(FlyBase, 1996-)

Additional comments

Source for merge of Haspin CG40080 was a shared cDNA ( date:030728 ).

(FlyBase, 1996-)

Source for merge of Haspin BcDNA:LD07633 was a shared cDNA ( date:030206 ).

(FlyBase, 1996-)

Nomenclature History

Source for database identify of

Nomenclature comments

Etymology

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

BcDNA:LD07633

CG40080

(Meadows, 2018.10.31, Caizzi et al., 2016, Ni et al., 2011.7.19, Ni et al., 2010.12.1, Drosophila Heterochromatin Genome Project, 2007, Rossi et al., 2007)

HASPIN

(Kochendoerfer et al., 2021, Carty and Dunleavy, 2020, Dattoli et al., 2020)

Haspin

(Messina et al., 2022, Akhtar et al., 2021, Joseph and Lai, 2021, Wang et al., 2021, Funikov et al., 2020, Gene Disruption Project members, 2016-, Ashwal-Fluss et al., 2014, Sopko et al., 2014, Westholm et al., 2014, Kwon et al., 2013, Rodriguez et al., 2012, Coulthard et al., 2010)

haspin

(Fresán et al., 2020, Rossi et al., 2007)

Name Synonyms

Haspin

(Manning, 2001.10.11)

Secondary FlyBase IDs

FBgn0058080
FBgn0063167
FBan0040080

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 32 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

3355064

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

P83103

UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information

P83103

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

P83103

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0046706

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

3355064/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0046706

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0046706

FlyMine - An integrated database for Drosophila genomics

FBgn0046706

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG40080

MARRVEL_MODEL - MARRVEL (model organism gene)

3355064

Linkouts

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0046706

DroID - A comprehensive database of gene and protein interactions.

FBgn0046706

DRSC - Results frm RNAi screens

FBgn0046706

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0046706

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0046706

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG40080

Flygut - An atlas of the Drosophila adult midgut

FBgn0046706

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC011145

Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution

Interactive Fly

References (44)

The following external sites may use different assemblies or annotations than FlyBase.

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