Mob1, Dmob2
Please see the JBrowse view of Dmel\Mob2 for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.46
Tissue-specific extension of 3' UTRs observed during later stages (FBrf0218523, FBrf0219848); all variants may not be annotated
Interacts with and activates trc, also interacts with wts.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Mob2 using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Isoform-specific expression patterns are observed. Sex-specific expression of alternative transcripts observed.
JBrowse - Visual display of RNA-Seq signals
View Dmel\Mob2 in JBrowse3-36
3-30.0
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
dsRNA made from templates generated with primers directed against this gene used in a cell-based RNAi assay to identify components or modifiers of the JAK/STAT pathway.
Identification: on basis of sequence similarity to S. cerevisiae MOB1 (S000001368).
Identified with: GH06341 <up>FlyBase curator comment: EST subsequently found to be chimeric</up>.
Source for identity of: Mob2 CG11711
FlyBase curator comment: in FBrf0155435 the symbol "Mob1" is used to refer to the CG11711 annotation. However, in subsequent references (FBrf0173414, FBrf0188034), the authors use the symbol "Dmob2" to refer to the CG11711 annotation.