Please see the JBrowse view of Dmel\Larp7 for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.52
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Larp7 using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Comment: maternally deposited
Larp7 protein is expressed at all developmental stages but is differentially expressed in some tissues. In the eye disc, it is found predominantly in ommatidial clusters. In the wing disc, it is found in the region that will become the notum. Pan-nuclear expression (excluding nucleoli) is observed in salivary gland and fat body. Nucleolar localization is seen in gastric caecae and gut. Nuclear localization is also observed in adult ovarian egg chambers.
JBrowse - Visual display of RNA-Seq signals
View Dmel\Larp7 in JBrowse1-27
1-28.4
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
The mxc locus was previously reported to correspond to the CG12058 annotation, based on rescue data, which could not be repeated. Molecular data from 4 different mxc alleles indicates that the CG12058 annotation is unaffected in the mxc mutants, but that the coding sequence of the adjacent gene, CG12124, is affected in all 4 cases. Thus, mxc corresponds to the CG12124 annotation.
The mxc locus was previously reported to correspond to the CG12058 annotation, but this was found to be an error (see FBrf0206617). The CG12058 annotation has thus been split out into a separate gene from mxc in release 5.16 of the genome annotation and has been renamed "CG42569" to avoid confusion.
FlyBase curator comment: FBrf0129198 states that mxc corresponds to the CG12058 annotation, but this was later found to be an error (see FBrf0206617).
Source for identity of: Larp7 CG42569