Sly1, d-sly
Please see the JBrowse view of Dmel\Slh for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.47
655 (aa)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Slh using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Comment: maternally deposited
Comment: reported as salivary gland primordium
Slh transcripts are first detected in stage 14 embryos in the posterior midgut, esophagus, and salivary glands and remain in these tissues throughout the rest of embryogenesis.
JBrowse - Visual display of RNA-Seq signals
View Dmel\Slh in JBrowsePlease Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
S2 cells treated with dsRNA generated against this gene show reduced phagocytosis of Candida albicans compared to untreated cells.
dpp enhancers ignore the nearer Slh and oaf promoters while activating transposon promoters (P{PZ} insertion into oaf, oafE-32). This use of only some promoters in the region strongly supports the notion that promoter specificity is the overriding feature establishing the regulatory autonomy of these genes.
Source for merge of: Slh CG15393
Annotation CG3539 merged with annotation CG15393 in release 5.47 of the genome annotation; CG15393 corresponds to the 3' UTR of CG3539.