FlyBase Insertion Report: Dmel\P{GawB}MzVum

General Information

Symbol

Dmel\P{GawB}MzVum

Species

D. melanogaster

Name

FlyBase ID

FBti0037957

Feature type

transposable_element_insertion_site

Also Known As

MzVUM-Gal4, Vsx-Gal4

Description

Inserted Element

P{GawB}

LINE ID

Affected gene(s)

Scer\GAL4, Vsx2

Viability / fertility

Associated allele(s)

Scer\GAL4^Vsx1-MzVum

Stock availability

1 publicly available

Genomic Location

Chromosomal Location

X ( 5A5 )

Sequence Location

Target / Docking site

Member of Large Scale Dataset(s)

Dataset

Description

Detailed Mapping Data

Chromosome (arm)

Sequence Location

Orientation

Cytological location (computed by FlyBase)

Cytological location (reported)

5A5 (reported as inferred from sequence location)

(Landgraf et al., 2003)

Insertion into Natural transposon

Comments concerning location

Sequence Data

Flanking sequence

Inserted Element

Construct

P{GawB}

Size (Kb)

11.279

Component Allele(s)

Scer\GAL4^wB

w^+mW.hs

Molecular map

Affected Gene(s)

Insertion may affect gene

Scer\GAL4

(Hadjieconomou et al., 2011, Ting et al., 2011, Ting et al., 2011, Bottenberg et al., 2009, Erclik et al., 2008, Erclik et al., 2008, de Velasco et al., 2007, Wheeler et al., 2006, Sanchez-Soriano and Prokop, 2005, Sanchez-Soriano et al., 2005, Landgraf et al., 2003)

Vsx2

(Landgraf et al., 2003)

Variant Molecular Consequences

Phenotypic Data

Associated Allele

Phenotypic Data

Scer\GAL4^Vsx1-MzVum

Phenotypic Class Phenotype Manifest in Detailed Description

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 11 -- 12

visual primordium | restricted

(Valentino and Erclik, 2022)

embryonic stage 12 -- third instar larval stage

larval VUM neuron

(Landgraf et al., 2003)

embryonic stage 13

embryonic/larval pharynx

(Erclik et al., 2008)

larval outer optic anlage

(Erclik et al., 2008)

larval VUM motor neuron

(Wheeler et al., 2006)

pars intercerebralis primordium

(Erclik et al., 2008)

embryonic stage 13 -- 15

embryonic outer optic lobe primordium

(Valentino and Erclik, 2022)

embryonic stage 13 -- 16

pars intercerebralis primordium

(Hwang and Rulifson, 2011)

late embryonic stage

pars intercerebralis primordium

(de Velasco et al., 2007)

embryonic stage 17

larval VUM motor neuron

(Wheeler et al., 2006)

embryonic stage 17 -- third instar larval stage

larval VUM neuron

(Bottenberg et al., 2009)

first instar larval stage

larval pars intercerebralis

(de Velasco et al., 2007)

third instar larval stage

ventral group vA neuron

(Landgraf et al., 2003)

embryonic/larval brain | restricted

(Erclik et al., 2008, de Velasco et al., 2007)

outer optic anlage neuroblast

(Erclik et al., 2008)

lamina

(Erclik et al., 2008)

medulla

(Erclik et al., 2008)

larval outer optic anlage

(Erclik et al., 2008)

larval insulin secreting cell of pars intercerebralis

(de Velasco et al., 2007)

larval pars intercerebralis

(de Velasco et al., 2007)

pupal stage P5 -- P6

transmedullary neuron

(Ngo et al., 2017)

adult stage

medulla

(Erclik et al., 2008)

adult optic lobe neuron | subset

(Ting et al., 2011)

transmedullary neuron Tm5b

(Ting et al., 2011)

adult mushroom body

(Khan et al., 2015)

Additional Information

Statement

Reference

Drives expression in VUM neurons, neurons of the pars intercerebralis, embryonic visual and pars intercerbralis primordia, embryonic outer optic lobe primordium and larval outer optic anlage, and transmedullary neuron Tm5b.

(FlyBase Curators, 2017)

ScerGAL4^Vsx1-MzVum drives expression in all lobes of the adult mushroom body.

(Khan et al., 2015)

The reporter is observed throughout the third instar larval outer optic lobe, including cells of the outer optic anlage, outer neuroblasts, lamina and medulla but not in the lobula complex or eye disc.

(Erclik et al., 2008)

The reporter is observed in the embryonic pharynx, pars intercerebralis, outer optic anlage, and in the adult medulla.

(Erclik et al., 2008)

Expression assayed at stages 9, 11, 13, and 17. Expression may be continuous between assayed stages in some tissues.

(Wheeler et al., 2006)

Expression is observed in VUM motorneurons from embryonic stage 12 though third instar, in See diagram in Fig 4C of FBrf0160715.

(Landgraf et al., 2003)

Marker for

larval VUM neuron

(Landgraf et al., 2003)

Reflects expression of

Vsx1

(Erclik et al., 2008, Erclik et al., 2008, de Velasco et al., 2007)

Reporter construct used in assay

Mmus\Cd8a^UAS.cLa.EGFP

(Ting et al., 2011, de Velasco et al., 2007)

Data on Genetic Line

Line ID

Origin as a multiple insertion line

Progenitor(s) within the Genome

Related Aberration or Balancer

Aberration

Balancer

Stocks (1)

Bloomington

29031

w^* P{GawB}MzVum; Syn⁹⁷

External Crossreferences and Linkouts ( 0 )

Comments

Insertion 886bp upstream of Vsx2. The insertion reflects the expression of the Vsx1 gene located approximately 33kb from the insertion site.

(Erclik et al., 2008)

Insertion site is 886 base pairs upstream of Vsx2.

(Landgraf et al., 2003)

Synonyms and Secondary IDs (14)

Reported As

Symbol Synonym

DChx-Gal4

(Cardona et al., 2009)

MZVUM-Gal4

(Valentino and Erclik, 2022)

MzVUM-Gal4

(Erclik et al., 2017, Ting et al., 2011, Ting et al., 2011, Bottenberg et al., 2009, Erclik et al., 2008, Erclik et al., 2008, Wheeler et al., 2006, Sanchez-Soriano et al., 2005, Landgraf et al., 2003)

MzVum-Gal4

(Konstantinides et al., 2022, Erclik et al., 2017, Li et al., 2016, Hadjieconomou et al., 2011, Cardona et al., 2009, de Velasco et al., 2007, Sanchez-Soriano and Prokop, 2005, Landgraf et al., 2003)

MzVum-Gal4MzVUM-Gal4

(Landgraf et al., 2003)

MzvumGal4

(Khan et al., 2015)

P{GawB}MzVum

(Landgraf et al., 2003, FlyBase, 1992-)

VUM-Gal4

(Bottenberg et al., 2009)

Vsx-GAL4

(Douthit et al., 2021)

Vsx-Gal4

(Ngo et al., 2017)

Vsx1-Gal4

(Erclik et al., 2017)

VsxGAL4

(Gold and Brand, 2014)

mzVUM-GAL4

(Hwang and Rulifson, 2011)

vsx-Gal4

(Ray and Li, 2022)

Name Synonyms

Secondary FlyBase IDs

References (23)

Report Sections