FB2024_03 , released June 25, 2024
Aberration: Dmel\Df(2R)BSC601
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General Information
Symbol
Df(2R)BSC601
Species
D. melanogaster
Name
FlyBase ID
FBab0045520
Feature type
Computed Breakpoints include

[60A9-60A9];[60B1-60B1];

Genomic Maps
Sequence coordinates
2R:23,907,252..23,907,252 (Df(2R)BSC601:bk1)
2R:23,992,124..23,992,124 (Df(2R)BSC601:bk2)
Member of large scale dataset(s)
Dfs_BSC_set2

A set of ~800 largely isogenic deficiency stocks created by FLP-induced recombination between FRT-carrying transgenic insertions; molecularly defined deletion endpoints correspond to initial location of the progenitor insertions. Designed to fill gaps in deletion coverage and breakpoint placement; also used to replace older available deficiencies that have not been molecularly mapped.

Nature of Aberration
Cytological Order
Class of aberration (relative to wild type)
Class of aberration (relative to progenitor)
Breakpoints
Causes alleles
Carries alleles
Formalized genetic data
Genetic mapping information
Comments

Breakpoint based on progenitor insertion release 3 sequence coordinate 2R:19035692 , per R. Hoskins (Gene Disruption Project) personal communication, mapped forward to release 5.

Breakpoint from FlyBase's release 5 sequence location of progenitor insertion.

Comments on Cytology

The Gene Disruption project determined the insertion site of P{XP}d11424 to be Release 3 genomic coordinate 19035692 on arm 2R. This corresponds to 60B1 on the Release 3 and Release 5 genome maps. The predicted position of PBac{WH}Nap1f06242 on the Release 5 map is 60A9. Consequently, the cytological breakpoints of Df(2R)BSC601 are predicted to be 60A9;60B1.

Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations

As in wild type, Df(2R)BSC601 mutant flies do not exhibit paralysis in response to heat shock. However they do exhibit a decrease in heart rate, smaller end diastolic dimensions and a preserved systolic function.

Stocks (1)
Notes on Origin
Discoverer
 
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 

The presence of P+PBac{XP5.WH5}BSC601 was verified using the PCR methods and primers described in FBrf0175003.

Synonyms and Secondary IDs (2)
References (9)