FB2024_03 , released June 25, 2024
Allele: Dmel\ftz3
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General Information
Symbol
Dmel\ftz3
Species
D. melanogaster
Name
FlyBase ID
FBal0004808
Feature type
allele
Associated gene
Dmel\ftz
Associated Insertion(s)
Carried in Construct
Also Known As
ftzc15
Key Links
Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

Mutagen
ethyl methanesulfonate
(Pattatucci et al., 1991)
Progenitor genotype
Cytology

Polytene chromosomes normal.

(Pattatucci et al., 1991)
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      ftz[+]/ftz3 is an enhancer of visible phenotype of BEAF-32BID.UAS.Tag:HA,Tag:NLS(SV40-largeT), Scer\GAL4ey.PH

      (Roy et al., 2011)
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      ftz3 has epidermis phenotype, enhanceable by hbD1

      (Bender et al., 1987)

      ftz3 has nervous system phenotype, enhanceable by hbD1

      (Bender et al., 1987)
      Enhancer of
      Statement
      Reference

      ftz[+]/ftz3 is an enhancer of eye phenotype of BEAF-32BID.UAS.Tag:HA,Tag:NLS(SV40-largeT), Scer\GAL4ey.PH

      (Roy et al., 2011)

      ftz3 is an enhancer of phenotype of hbD1

      (Bender et al., 1987)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The rough eye phenotype of flies expressing BEAF-32BID.Scer\UAS.T:Ivir\HA1,T:SV40\nls2 under the control of Scer\GAL4ey.PH is enhanced by ftz3/+.

      (Roy et al., 2011)

      In double mutant with hbD1 segmentation defects approximate to the expectations of simple additivity of the two mutants but the cuticular element defects and nervous system defects are more severe.

      (Bender et al., 1987)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      ftz3 is rescued by ftz+t10.8

      (Roy et al., 2011)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Cain.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ftz3
      (Kuzin et al., 2011, Roy et al., 2011)
      ftzc15
      (Pattatucci et al., 1991, Bender et al., 1987)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)