FB2024_03 , released June 25, 2024
Allele: Dmel\vari38EFa2
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General Information
Symbol
Dmel\vari38EFa2
Species
D. melanogaster
Name
FlyBase ID
FBal0091364
Feature type
allele
Associated gene
Dmel\vari
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Kozlova et al., 1998)
Progenitor genotype
Cytology
Description

Mutation in the splice acceptor site of exon 3.

(Bachmann et al., 2008)

Mutation in the first common intron splice acceptor site.

(Wu et al., 2007)

Nucleotide substitution: G?A.

(Wu et al., 2007)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2L:20,792,267..20,792,267 [-]
Nucleotide change:

G20792267A

Reported nucleotide change:

G?A

Comment:

G to A mutation in the first common intron splice acceptor site.

(Wu et al., 2007)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutants do not show defects in septate junction barrier function (as tested using a dye exclusion assay).

      Mutants have mild tracheal defects.

      (Wu et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      38EFa2
      (Wu et al., 2007)
      l(2)38EFa2
      vari38EFa2
      (Bachmann et al., 2008)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)