Amino acid replacement: R185C.
Nucleotide substitution: ??T.
C20790453T
??T
R352C | vari-PB; R185C | vari-PC; R331C | vari-PD; R352C | vari-PE; R185C | vari-PF
R185C
Mutants show defects in septate junction barrier function (as tested using a dye exclusion assay).
Mutants have strong tracheal defects.