FlyBase Allele Report: Dmel\cv-2[EP1103]

General Information

Symbol

Dmel\cv-2^EP1103

Species

D. melanogaster

Name

FlyBase ID

FBal0120522

Feature type

allele

Associated gene

Dmel\cv-2

Associated Insertion(s)

P{EP}cv-2^EP1103

Carried in Construct

Also Known As

EP(2)1103

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Gene Disruption Project members, 2001-, Conley et al., 2000)

Progenitor genotype

Associated Insertion(s)

P{EP}cv-2^EP1103

Cytology

Description

P{EP} insertion upstream of cv-2.

(Conley et al., 2000)

Allele components

Component

Use(s)

Inserted element

P{EP}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2R:21,379,500..21,379,500 [-]

(Serpe et al., 2008, Ralston and Blair, 2005, Gene Disruption Project members, 2001-, Conley et al., 2000)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

viable

(Conley et al., 2000)

Phenotype Manifest In

anterior crossvein | ectopic, with Scer\GAL4^ap-md52

(Conley et al., 2000)

posterior crossvein, with Scer\GAL4^ap-md52

(Conley et al., 2000)

wing vein, with Scer\GAL4^ap-md52

(Conley et al., 2000)

wing vein | ectopic, with Scer\GAL4^ap-md52

(Conley et al., 2000)

Detailed Description

Statement

Reference

Posterior cross vein formation is normal when cv-2^EP1103 is expressed under the control of Scer\GAL4^en-e16E.

(Serpe et al., 2008)

Overexpression of cv-2^EP1103 in the posterior compartment of the wing, under the control of Scer\GAL4^en-e16E, does not affect crossvein formation.

(Ralston and Blair, 2005)

Homozygotes have wild-type wings. When expression of cv-2^EP1103 is driven by Scer\GAL4^ap-md52, a number of wing phenotypes are seen. The most severely affected wings have ectopic venation near wing vein L2, vein deltas at the tips of then longitudinal veins, thickening of the anterior crossvein. Occasionally partial loss of the posterior crossvein is seen.

(Conley et al., 2000)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

cv^EP1349, cv-2^EP1103, sog^UAS.Tag:HA, Scer\GAL4^A9 is a suppressor of visible | adult stage phenotype of Gyc76C^GD48, Scer\GAL4^A9

(Schleede and Blair, 2015)

NOT Suppressor of

Statement

Reference

cv-2^EP1103, Scer\GAL4^A9 is a non-suppressor of visible | adult stage phenotype of Gyc76C^GD48, Scer\GAL4^A9

(Schleede and Blair, 2015)

cv-2^EP1103/sog^UAS.Tag:HA, Scer\GAL4^A9 is a non-suppressor of visible | adult stage phenotype of Gyc76C^GD48, Scer\GAL4^A9

(Schleede and Blair, 2015)

cv^EP1349/cv-2^EP1103, Scer\GAL4^A9 is a non-suppressor of visible | adult stage phenotype of Gyc76C^GD48, Scer\GAL4^A9

(Schleede and Blair, 2015)

Phenotype Manifest In

Suppressor of

Statement

Reference

cv^EP1349, cv-2^EP1103, sog^UAS.Tag:HA, Scer\GAL4^A9 is a suppressor of wing blade phenotype of Gyc76C^GD48, Scer\GAL4^A9

(Schleede and Blair, 2015)

cv^EP1349, cv-2^EP1103, sog^UAS.Tag:HA, Scer\GAL4^A9 is a suppressor of posterior crossvein phenotype of Gyc76C^GD48, Scer\GAL4^A9

(Schleede and Blair, 2015)

Scer\GAL4^en-e16E/cv-2^EP1103 is a suppressor of crossvein phenotype of Scer\GAL4^en-e16E, sog^UAS.cYa

(Ralston and Blair, 2005)

NOT Suppressor of

Statement

Reference

cv-2^EP1103, Scer\GAL4^A9 is a non-suppressor of wing blade phenotype of Gyc76C^GD48, Scer\GAL4^A9

(Schleede and Blair, 2015)

cv-2^EP1103, Scer\GAL4^A9 is a non-suppressor of posterior crossvein phenotype of Gyc76C^GD48, Scer\GAL4^A9

(Schleede and Blair, 2015)

cv-2^EP1103/sog^UAS.Tag:HA, Scer\GAL4^A9 is a non-suppressor of wing blade phenotype of Gyc76C^GD48, Scer\GAL4^A9

(Schleede and Blair, 2015)

cv-2^EP1103/sog^UAS.Tag:HA, Scer\GAL4^A9 is a non-suppressor of posterior crossvein phenotype of Gyc76C^GD48, Scer\GAL4^A9

(Schleede and Blair, 2015)

cv^EP1349/cv-2^EP1103, Scer\GAL4^A9 is a non-suppressor of wing blade phenotype of Gyc76C^GD48, Scer\GAL4^A9

(Schleede and Blair, 2015)

cv^EP1349/cv-2^EP1103, Scer\GAL4^A9 is a non-suppressor of posterior crossvein phenotype of Gyc76C^GD48, Scer\GAL4^A9

(Schleede and Blair, 2015)

Additional Comments

Genetic Interactions

Statement

Reference

The disruption of the posterior crossvein characteristic for flies expressing Gyc76C^GD48 under the control of Scer\GAL4^A9 is not improved by co-expression of cv-2^EP1103, sog^{Scer\UAS.T:Ivir\HA1}, nor by the a combination of sog^{Scer\UAS.T:Ivir\HA1} and cv-2^EP1103 but it is rescued by triple co-expression of sog^{Scer\UAS.T:Ivir\HA1}, cv^EP1349 and cv-2^EP1103.

(Schleede and Blair, 2015)

The loss of crossvein phenotype can be rescued when cv-2^EP1103 is expressed under the control of Scer\GAL4^en-e16E, along with sog^Scer\UAS.cYa expression.

(Ralston and Blair, 2005)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Complements

cv-2^unspecified

(Conley et al., 2000)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

cv-2^EP1103

(Schleede and Blair, 2015)

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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