FlyBase Allele Report: Scer\GAL4[Myc-PG45]

General Information

Symbol

Scer\GAL4^Myc-PG45

Species

S. cerevisiae

Name

FlyBase ID

FBal0130659

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

P{GawB}Myc^PG45

Carried in Construct

Also Known As

PG45

Allele class

Mutagen

Delta2-3 transposase

Nature of the Allele

Allele class

Mutagen

Delta2-3 transposase

(Bourbon et al., 2002)

Progenitor genotype

Associated Insertion(s)

P{GawB}Myc^PG45

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{GawB}

enhancer trap

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage | female & oogenesis

follicle cell

(Zappia et al., 2011, Elalayli et al., 2008)

Additional Information

Statement

Reference

ScerGAL4^Myc-PG45 drives expression in a pattern similar to that of native Myc expression.

(Benassayag et al., 2005)

Marker for

Reflects expression of

Myc

(Zappia et al., 2011, Elalayli et al., 2008, Benassayag et al., 2005)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

female semi-sterile | heat sensitive, with M6^KK109436, Scer\GAL80^ts.αTub84B

(Zappia et al., 2011)

female sterile | heat sensitive, with M6^NIG.7540R, Scer\GAL80^ts.αTub84B

(Zappia et al., 2011)

lethal | heat sensitive, with Hsap\MYC^UAS.1

(Benassayag et al., 2005)

lethal | heat sensitive, with Hsap\MYC^UAS.2

(Benassayag et al., 2005)

lethal | heat sensitive, with Myc^UAS.cZa

(Benassayag et al., 2005)

lethal - all die during embryonic stage, with psd^RNAi.UAS

(Elalayli et al., 2008)

some die during embryonic stage, with psd^RNAi.UAS

(Elalayli et al., 2008)

viable, with Hsap\MYC^UAS.S

(Benassayag et al., 2005)

Phenotype Manifest In

border follicle cell | heat sensitive, with M6^KK109436, Scer\GAL80^ts.αTub84B

(Zappia et al., 2011)

cortical actin cytoskeleton & oocyte, with psd^RNAi.UAS

(Elalayli et al., 2008)

egg | heat sensitive, with M6^KK109436, Scer\GAL80^ts.αTub84B

(Zappia et al., 2011)

egg | heat sensitive, with M6^NIG.7540R, Scer\GAL80^ts.αTub84B

(Zappia et al., 2011)

egg chamber | heat sensitive, with M6^KK109436, Scer\GAL80^ts.αTub84B

(Zappia et al., 2011)

follicle cell | heat sensitive, with M6^NIG.7540R, Scer\GAL80^ts.αTub84B

(Zappia et al., 2011)

microvillus & follicle cell, with psd^RNAi.UAS

(Elalayli et al., 2008)

vitelline membrane, with psd^RNAi.UAS

(Elalayli et al., 2008)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Scer\GAL4^Myc-PG45/Hsap\MYC^UAS.2 is a suppressor | partially of lethal phenotype of Myc^PG45

(Benassayag et al., 2005)

Scer\GAL4^Myc-PG45/Hsap\MYC^UAS.S is a suppressor | partially of lethal phenotype of Myc^PG45

(Benassayag et al., 2005)

Scer\GAL4^Myc-PG45/Hsap\MYC^UAS.2 is a suppressor | cell autonomous | somatic clone of decreased cell growth rate | somatic clone phenotype of Myc^PG45

(Benassayag et al., 2005)

Scer\GAL4^Myc-PG45/Hsap\MYC^UAS.S is a suppressor | cell autonomous | partially | somatic clone of decreased cell growth rate | somatic clone phenotype of Myc^PG45

(Benassayag et al., 2005)

NOT Suppressor of

Statement

Reference

Scer\GAL4^Myc-PG45/Hsap\MYC^UAS.1 is a non-suppressor of lethal phenotype of Myc^PG45

(Benassayag et al., 2005)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^Myc-PG45/Myc^{ΔN.UAS.Tag:HA} rescues Myc^PG45