FlyBase Allele Report: Dmel\Pen[UAS.cMa]

General Information

Symbol

Dmel\Pen^UAS.cMa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Mason

FlyBase ID

FBal0137396

Feature type

allele

Associated gene

Dmel\Pen

Associated Insertion(s)

Carried in Construct

P{UAS-Pen.M}

Key Links

Transgenic product class

wild_type

(Mason et al., 2002)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Mason et al., 2002)

Mutagen

in vitro construct

(Mason et al., 2002)

Progenitor genotype

Carried in construct

P{UAS-Pen.M}

Cytology

Description

UASt regulatory sequences drive expression of Pen.

(Mason et al., 2002)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Pen

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

viable, with Scer\GAL4^e22c

(Ratan et al., 2008)

Phenotype Manifest In

Detailed Description

Statement

Reference

Expression of Pen^Scer\UAS.cMa under the control of Scer\GAL4^e22c does not result in lethality or defects in the adult abdomen.

(Ratan et al., 2008)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^how-24B/Pen^UAS.cMa rescues Pen^D14

(Mosca and Schwarz, 2010)

Partially rescues

Pen^UAS.cMa/Scer\GAL4^hs.PB partially rescues Pen^D14

(Mason et al., 2002)

Fails to rescue

Scer\GAL4^elav.PLu/Pen^UAS.cMa fails to rescue Pen^D14

(Mosca and Schwarz, 2010)

Comments

Expression of Pen^Scer\UAS.cMa under the control of Scer\GAL4^how-24B largely rescues the somatic muscle patterning defects seen in Pen^D14 larvae.

Expression of Pen^Scer\UAS.cMa under the control of Scer\GAL4^elav.PLu does not rescue the somatic muscle patterning defects seen in Pen^D14 larvae.

(Mosca and Schwarz, 2010)

Expression of Pen^Scer\UAS.cMa under the control of Scer\GAL4^hs.PB using heat shock partially rescues the sterility of Pen^D14 males.

(Mason et al., 2002)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Pen^Scer\UAS.cMa

Pen^UAS.cMa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Mason

(Mason et al., 2002)

Secondary FlyBase IDs

References (3)

Report Sections

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