FB2024_03 , released June 25, 2024
Allele: Dmel\Kap-α3UAS.cMa
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General Information
Symbol
Dmel\Kap-α3UAS.cMa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Mason
FlyBase ID
FBal0137473
Feature type
allele
Associated gene
Dmel\Kap-α3
Associated Insertion(s)
Carried in Construct
P{UAS-Kap-α3.M}
Key Links
Transgenic product class
wild_type
(Mason et al., 2002)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Mason et al., 2002)
Mutagen
in vitro construct
(Mason et al., 2002)
Progenitor genotype
Carried in construct
P{UAS-Kap-α3.M}
Cytology
Description

UASt regulatory sequences drive expression of Kap-α3.

(Mason et al., 2002)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Kap-α3
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Kap-α3Scer\UAS.cMa under the control of Scer\GAL4e22c at 25[o]C results in partial lethality. Surviving adult escapers show a defect in abdominal development; in 65% of flies, the adult hemitergites fail to properly fuse at the dorsal midline.

      Expression of Kap-α3Scer\UAS.cMa under the control of Scer\GAL4e22c at 27.5[o]C results in almost complete lethality.

      (Ratan et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Scer\GAL4hs.PB/Kap-α3UAS.cMa is a suppressor of male sterile | recessive phenotype of PenD14

      (Mason et al., 2002)
      NOT Suppressor of
      Statement
      Reference

      Scer\GAL4VP16.nanos.UTR/Kap-α3UAS.cMa is a non-suppressor of female sterile | recessive phenotype of PenD14

      (Mason et al., 2002)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of Kap-α3Scer\UAS.cMa under the control of Scer\GAL4hs.PB using heat shock partially rescues the sterility of PenD14 males.

      (Mason et al., 2002)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Kap-α3Scer\UAS.cMa
      Kap-α3UAS.cMa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Mason
      (Mason et al., 2002)
      Secondary FlyBase IDs
        References (3)