The expression of Ilp6^HMS00549 under the control of Scer\GAL4^r4 induces a significant increase in wing size, despite of no size changes in the wing disc.

Expression of Ilp6^Scer\UAS.cIa in the insulin producing cells (IPCs) under the control of Scer\GAL4^Ilp2.PR ameliorates both the lethality and developmental delay phenotypes associated with developmental ethanol exposure. Expression of Ilp6^Scer\UAS.cIa under the control of Scer\GAL4^Ilp2.PR completely rescues the increased resistance to sedation seen in wild type larvae raised on 5% ethanol. The reduction in ability to develop tolerance is not rescued.

Central nervous system neuroblasts of fed second instar larvae expressing Ilp6^Scer\UAS.cIa under the control of either Scer\GAL4^repo.PU or Scer\GAL4^n-syb.PS show an increase in EdU incorporation compared to controls.

Central nervous system neuroblasts of larvae expressing Ilp6^Scer\UAS.cIa under the control of Scer\GAL4^n-syb.PS and raised on a diet lacking amino acids for 24 hours show an increase in EdU incorporation compared to controls.

Central nervous system neuroblasts of larvae expressing Ilp6^Scer\UAS.cIa under the control of Scer\GAL4^Ubx.PU and raised on a diet lacking amino acids for 24 hours show an increase in EdU incorporation compared to controls. This reactivation of the neuroblasts indicated by the EdU incorporation occurs in the normal spatial pattern.

Expression of Ilp6^Scer\UAS.cIa under the control of Scer\GAL4^repo.PU does not affect the body mass of third instar larvae.

Expression of Ilp6^Scer\UAS.cIa under the control of Scer\GAL4^Lsp2.PH results in an increase in body weight compared to controls.

Expression of Ilp6^Scer\UAS.cIa under the control of Scer\GAL4^Cg.PA results in adults with a larger body mass than controls.

Adults in which expression of Ilp6^Scer\UAS.cIa under the control of Scer\GAL4^Act occurs up to 96 hours after egg deposition (AED) have a normal mass. However, animals in which which expression of Ilp6^Scer\UAS.cIa under the control of Scer\GAL4^Act occurs up to 120 hours AED have an increased mass compared to control animals. Adults in which Ilp6^Scer\UAS.cIa has been expressed under the control of Scer\GAL4^Act from 120 hours AED until adult emergence show reduced resistance to starvation compared to controls. The adults have reduced levels of glycogen compared to controls. (In all these experiments, the temperature sensitive Scer\GAL80^ts.αTub84B allele has been used to control the activity of the Scer\GAL4 driver).

When Ilp6^Scer\UAS.cIa is driven by Scer\GAL4^arm.PS or Scer\GAL4^Act5C.PP a statistically significant increase in body size is seen.

Ilp6^UAS.cIa, Scer\GAL4^r4 has abnormal size | adult stage phenotype, enhanceable by Tl^{10b.UAS.Tag:MYC}, Scer\GAL4^r4

Ilp6^UAS.cIa, Scer\GAL4^r4 has visible | adult stage phenotype, enhanceable by Tl^{10b.UAS.Tag:MYC}, Scer\GAL4^r4

Ilp6^UAS.cIa, Scer\GAL4^r4 is a suppressor | partially of abnormal size | adult stage phenotype of Scer\GAL4^r4, Tl^{10b.UAS.Tag:MYC}

Ilp6^UAS.cIa, Scer\GAL4^r4 is a suppressor | partially of visible | adult stage phenotype of Scer\GAL4^r4, Tl^{10b.UAS.Tag:MYC}

Ilp6^UAS.cIa, Scer\GAL4^r4 is a suppressor | partially of partially lethal - majority die phenotype of Scer\GAL4^r4, Tl^{10b.UAS.Tag:MYC}

Ilp6^UAS.cIa, Scer\GAL4^r4 is a suppressor of abnormal size | larval stage phenotype of Scer\GAL4^r4, Tl^{10b.UAS.Tag:MYC}

Ilp6^UAS.cIa, Scer\GAL4^r4 is a suppressor | partially of wing phenotype of Scer\GAL4^r4, Tl^{10b.UAS.Tag:MYC}

Ilp6^UAS.cIa, Scer\GAL4^r4 is a suppressor of wing disc phenotype of Scer\GAL4^r4, Tl^{10b.UAS.Tag:MYC}