FlyBase Allele Report: Dmel\Ask1[UAS.Tag:FLAG]

General Information

Symbol

Dmel\Ask1^UAS.Tag:FLAG

Species

D. melanogaster

Name

FlyBase ID

FBal0152300

Feature type

allele

Associated gene

Dmel\Ask1

Associated Insertion(s)

Carried in Construct

P{UAS-Ask1.FLAG}

Key Links

Transgenic product class

wild_type

(Kuranaga et al., 2002)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Kuranaga et al., 2002)

Mutagen

in vitro construct

(Kuranaga et al., 2002)

Progenitor genotype

Ask1^GMR.PK

(Kuranaga et al., 2002)

Carried in construct

P{UAS-Ask1.FLAG}

Cytology

Description

Expression of Ask1 fused to the epitope tag Tag:FLAG, is under the control of UASt sequences.

(Kuranaga et al., 2002)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Ask1

Tagged with

Tag:FLAG

epitope tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

Expression of Pk92B^{Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^pnr-MD237 does not result in an increase in melanisation of the adult thorax cuticle.

(Sekine et al., 2012)

Overexpression of Pk92B^{Scer\UAS.T:Zzzz\FLAG}, under the regulation of Scer\GAL4^ap-md544 has no effect on thorax closure.

(Cha et al., 2005)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Ask1^UAS.Tag:FLAG, Scer\GAL4^pnr-MD237 is an enhancer of abnormal body color phenotype of Scer\GAL4^pnr-MD237, slim^GS10238

(Sekine et al., 2012)

Phenotype Manifest In

Enhancer of

Statement

Reference

Ask1^UAS.Tag:FLAG, Scer\GAL4^pnr-MD237 is an enhancer of adult cuticle phenotype of Scer\GAL4^pnr-MD237, slim^GS10238

(Sekine et al., 2012)

Suppressor of

Statement

Reference

Ask1^UAS.Tag:FLAG, Scer\GAL4^ap-md544 is a suppressor | partially of adult thorax phenotype of Scer\GAL4^ap-md544, park^UAS.Tag:MYC

(Cha et al., 2005)

Ask1^UAS.Tag:FLAG, Scer\GAL4^ap-md544 is a suppressor of mesothoracic cleft | ectopic phenotype of Scer\GAL4^ap-md544, park^UAS.Tag:MYC

(Cha et al., 2005)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of Pk92B^{Scer\UAS.T:Zzzz\FLAG} enhances the melanisation of the adult thorax cuticle seen in flies expressing slim^GS10238 under the control of Scer\GAL4^pnr-MD237.

(Sekine et al., 2012)

Overexpression of Pk92B^{Scer\UAS.T:Zzzz\FLAG} and park^{Scer\UAS.T:Hsap\MYC} in the notum of wing imaginal discs, under the regulation of Scer\GAL4^ap-md544 partially suppresses the thoracic cleft observed in park^{Scer\UAS.T:Hsap\MYC} mutants.

(Cha et al., 2005)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Ask1^{Scer\UAS.T:Zzzz\FLAG}

Ask1^UAS.Tag:FLAG

Pk92B^{Scer\UAS.T:Zzzz\FLAG}

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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