FB2024_03 , released June 25, 2024
Allele: Dmel\AxnEY10228
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General Information
Symbol
Dmel\AxnEY10228
Species
D. melanogaster
Name
FlyBase ID
FBal0162780
Feature type
allele
Associated gene
Dmel\Axn
Associated Insertion(s)
P{EPgy2}AxnEY10228
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Gene Disruption Project members, 2001-)
Progenitor genotype
Associated Insertion(s)
P{EPgy2}AxnEY10228
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{EPgy2}
Regulatory region(s)
UASp
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      AxnEY10228 is an enhancer of increased cell death | somatic clone phenotype of Rbf15aΔ

      (Zhang et al., 2014)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      AxnEY10228 is an enhancer of eye disc | somatic clone phenotype of Rbf15aΔ

      (Zhang et al., 2014)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      AxnEY10228 enhances the increase in apoptosis anterior to the morphogenetic furrow seen in Rbf15aΔ mutant eye disc clones. Apoptosis is seen both anterior and posterior to the morphogenetic furrow in the double mutants.

      (Zhang et al., 2014)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      AxnEY10228
      (Zhang et al., 2017, Abdou et al., 2011)
      axnEY10228
      (Zhang et al., 2014)
      axnEY
      (Zhang et al., 2014)
      Name Synonyms
      Secondary FlyBase IDs
        References (6)