FB2024_03 , released June 25, 2024
Allele: Dmel\dlg1S97N.UAS.EGFP
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General Information
Symbol
Dmel\dlg1S97N.UAS.EGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0180200
Feature type
allele
Associated gene
Dmel\dlg1
Associated Insertion(s)
Carried in Construct
P{UAS-dlg1.S97N-EGFP}
Also Known As
UAS-EGFP-dlgS97
Key Links
Transgenic product class
wild_type
(Bachmann et al., 2004)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Bachmann et al., 2004)
Mutagen
in vitro construct
(Bachmann et al., 2004)
Progenitor genotype
Carried in construct
P{UAS-dlg1.S97N-EGFP}
Cytology
Description

UASt regulatory sequences drive expression of the entire coding region of dlg1 EST LP07807 (encoding the short dlg1-S97N isoform) fused at the C-terminal end to EGFP.

(Bachmann et al., 2004)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
dlg1
Tagged with
EGFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of dlg1S97N.Scer\UAS.T:Avic\GFP-EGFP under the control of Scer\GAL4c747 does not significantly affect tolerance to ethanol vapor-induced sedation as compared to controls.

      (Maiya et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4elav-C155/dlg1S97N.UAS.EGFP rescues dlg1S97-5

      (Mendoza-Topaz et al., 2008)
      Partially rescues

      Scer\GAL4c747/dlg1S97N.UAS.EGFP partially rescues dlg1intol

      (Maiya et al., 2012)
      Fails to rescue

      Scer\GAL4dlg1-intol/dlg1S97N.UAS.EGFP fails to rescue dlg1intol

      (Maiya et al., 2012)
      Comments

      Expression of dlg1S97N.Scer\UAS.T:Avic\GFP-EGFP under the control of Scer\GAL4c747, but not Scer\GAL4dlg1-intol, partially rescues the defective ethanol tolerance of dlg1intol/dlg1intol mutants.

      (Maiya et al., 2012)

      Courtship behaviour defects seen in dlg1S97-5 homozygotes are completely rescued by the expression of dlg1S97N.Scer\UAS.T:Avic\GFP-EGFP under the control of Scer\GAL4elav-C155.

      Circadian locomotor behavior defects seen in dlg1S97-138 homozygotes are rescued by expression of dlg1S97N.Scer\UAS.T:Avic\GFP-EGFP under the control of Scer\GAL4elav-C155.

      (Mendoza-Topaz et al., 2008)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      dlg1S97N.Scer\UAS.T:Avic\GFP-EGFP
      dlg1S97N.UAS.EGFP
      Name Synonyms
      Secondary FlyBase IDs
        References (7)