Expression of Gr21aScer\UAS.cJa under the control of Scer\GAL4Or22a.7.717 does not confer CO2 responsiveness onto ab3A neurons.
Scer\GAL4Ir64a.PA, Gr63aUAS.cJa, Gr21aUAS.cJa is a suppressor of abnormal smell perception | recessive phenotype of Gr63a1, Ir64aMB05283
Expression of both Gr63aScer\UAS.cJa and Gr21aScer\UAS.cJa under the control of Scer\GAL4Ir64a.PA in Ir64aMB05283, Gr63a1 double mutant flies allows artificial stimulation of DC4 dorsal glomeruli of the adult antennal lobe by 5% CO[[2]] and robust avoidance of CO[[2]] in behavioural experiments. However, DP1m neurons are not activated by CO[[2]] in these mutants.
Coexpression of Gr21aScer\UAS.cJa and Gr63aScer\UAS.cJa under the control of Scer\GAL4Or22a.7.717 confers CO2 responsiveness on ab3A neurons, a type of neuron that is normally unresponsive to CO2. This is in contrast to expression of either UAS transgene alone or in combination with Gr10aScer\UAS.cJa, where CO2 responsiveness is not conferred.