FlyBase Allele Report: Dmel\cysu[GD6190]

General Information

Symbol

Dmel\cysu^GD6190

Species

D. melanogaster

Name

FlyBase ID

FBal0204858

Feature type

allele

Associated gene

Dmel\cysu

Associated Insertion(s)

Carried in Construct

P{GD6190}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Dickson et al., 2007.7.18)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Dickson et al., 2007.7.18)

Mutagen

in vitro construct

(Dickson et al., 2007.7.18)

Progenitor genotype

Carried in construct

P{GD6190}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Dickson et al., 2007.7.18)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-GD6190

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

short lived, with Scer\GAL4^Act5C.PU

(Bailey et al., 2017)

short lived, with Scer\GAL4^da.PU

(Bailey et al., 2017)

short lived, with Scer\GAL4^Tub.PU

(Bailey et al., 2017)

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

(Neely et al., 2010)

viable, with Scer\GAL4^Mef2.PR

(Schnorrer et al., 2010)

viable, with Scer\GAL4^pnr-MD237

(Mummery-Widmer et al., 2009)

visible, with Scer\GAL4^ap.PU

(Hurd et al., 2015)

visible, with Scer\GAL4^pnr-MD237

(Mummery-Widmer et al., 2009)

visible | adult stage, with Scer\GAL4^Act.PU

(Bailey et al., 2017)

visible | adult stage, with Scer\GAL4^en.PU

(Bailey et al., 2017)

visible | adult stage, with Scer\GAL4^esg.PU

(Bailey et al., 2017)

Phenotype Manifest In

mesothoracic tergum, with Scer\GAL4^pnr-MD237

(Mummery-Widmer et al., 2009)

wing, with Scer\GAL4^Act.PU

(Bailey et al., 2017)

wing, with Scer\GAL4^ap.PU

(Hurd et al., 2015)

wing, with Scer\GAL4^esg.PU

(Bailey et al., 2017)

wing posterior compartment, with Scer\GAL4^en.PU

(Bailey et al., 2017)

Detailed Description

Statement

Reference

Expression of cysu^GD6190 under the control of Scer\GAL4^ap.PU results in slight downturn and cupping of the wing.

(Hurd et al., 2015)

Expression of cysu^GD6190 under the control of Scer\GAL4^sal.BO (in combination with a Dicer-2 transgene to enhance RNAi efficiency) does not result in larval lethality at the L2/L3 transition.

(Wicker-Thomas et al., 2015)

Adults expressing CG5873^GD6190 under the control of Scer\GAL4^elav.PLu (in the presence of Dcr-2^Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.

(Neely et al., 2010)

Expression under the control of Scer\GAL4^pnr-MD237 results in an enlarged notum.

(Mummery-Widmer et al., 2009)

External Data

Linkouts

Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development

6190

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

cysu^GD6190/Scer\GAL4^ap.PU is a suppressor of visible | dominant phenotype of Duox^K

(Hurd et al., 2015)

Phenotype Manifest In

Suppressor of

Statement

Reference

cysu^GD6190/Scer\GAL4^ap.PU is a suppressor of wing phenotype of Duox^K

(Hurd et al., 2015)

Additional Comments

Genetic Interactions

Statement

Reference

Expression of cysu^GD6190 under the control of Scer\GAL4^ap.PU fully suppresses the 'Curly' wing phenotype (upward curvature of the wing) of Cy^K heterozygotes.

(Hurd et al., 2015)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v14374

w¹¹¹⁸; P{GD6190}v14374

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 1 )

Linkouts

Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development

6190

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

CG5873^GD6190

cysu^GD6190

Name Synonyms

Secondary FlyBase IDs

References (8)

Report Sections

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