FB2024_03 , released June 25, 2024
Allele: Dmel\TSG101GD14295
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General Information
Symbol
Dmel\TSG101GD14295
Species
D. melanogaster
Name
FlyBase ID
FBal0208701
Feature type
allele
Associated gene
Dmel\TSG101
Associated Insertion(s)
Carried in Construct
P{GD14295}
Also Known As
Tsg101 RNAi
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Dickson et al., 2007.7.18)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Dickson et al., 2007.7.18)
Mutagen
in vitro construct
(Dickson et al., 2007.7.18)
Progenitor genotype
Carried in construct
P{GD14295}
Cytology
Description

UASt regulatory sequences drive expression of an inverted repeat.

(Dickson et al., 2007.7.18)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
dsRNA-GD14295
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The cell size in pupal (2hr after pupariation) midgut somatic clones expressing TSG101GD14295 under the control of Scer\GAL4Scer\FRT.Rnor\Cd2.Act5C is significantly increased but the cells contain fewer Atg8a puncta compared to control cells.

      (Anding et al., 2018)

      The expression of TSG101GD14295 under the control of Scer\GAL4c564 does not lead to significant changes in the average adult fat body cell size, as compared to controls.

      (Neyen et al., 2016)

      Expression of Scer\GAL4C-765>TSG101GD14295 does not induce any obvious abnormalities.

      (Fan et al., 2013)

      Expression under the control of Scer\GAL4Mef2.PR results in late pupal lethality.

      (Schnorrer et al., 2010)
      External Data
      Linkouts
      Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      TSG101GD14295/Scer\GAL4C-765 is an enhancer of visible phenotype of Scer\GAL4C-765, smoPKA12.UAS

      (Fan et al., 2013)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The co-expression of TSG101GD14295 and pnutGD1512 from the second instar larval stage under the combined control of Scer\GAL4ap-md544 and Gal80[ts] does not leads to the formation of tumors in the third instar larval wing disc.

      (Gerlach et al., 2018)

      Co-expression of TSG101GD14295 with smoPKA12.Scer\UAS under the control of Scer\GAL4C-765 enhances the wing vein fusion phenotype resulting from the expression of smoPKA12.Scer\UAS.

      (Fan et al., 2013)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 1 )
      Linkouts
      Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      TSG101GD14295
      Name Synonyms
      Secondary FlyBase IDs
        References (12)