UASt regulatory sequences drive expression of an inverted repeat.
Expression of upd3GD6811 under the control of Scer\GAL4esg.PU or Scer\GAL4NP0001, in combination with a Gal80[ts] transgene to restrict expression to the adult stage, does not cause any obvious midgut phenotypes, compared to controls.
Adults expressing upd3GD6811 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.
upd3GD6811, Scer\GAL4NP0001 is a suppressor of increased occurrence of cell division | adult stage phenotype of Ets21CUAS.LONG.Tag:MYC, Scer\GAL4NP0001
upd3GD6811/Scer\GAL4NP0001 is a suppressor of increased cell number phenotype of Scer\GAL4NP0001, ebd1JF02926
upd3GD6811/Scer\GAL4NP0001 is a suppressor of increased occurrence of cell division | adult stage phenotype of Tnks503/Tnks19
upd3GD6811/Scer\GAL4NP0001 is a suppressor of increased cell number | adult stage phenotype of Tnks503/Tnks19
upd3GD6811/Scer\GAL4srp.D.cCa, Scer\GAL80ts.αTub84B is a suppressor | heat sensitive of melanotic mass phenotype | heat sensitive phenotype of Scer\GAL4srp.D.cCa, Scer\GAL80ts.αTub84B, gcmDN.UAS
upd3GD6811, Scer\GAL4ap-md544 is a non-suppressor of abnormal developmental rate phenotype of BacA\p35UAS.cHa, Bub3GD9924, Scer\GAL4ap-md544
Scer\GAL4ap-md544, upd3GD6811/Ilp8GD1670 is a non-suppressor of abnormal developmental rate phenotype of BacA\p35UAS.cHa, Bub3GD9924, Scer\GAL4ap-md544
Scer\GAL4ap-md544, upd3GD6811/NLazKK107553 is a non-suppressor of abnormal developmental rate phenotype of BacA\p35UAS.cHa, Bub3GD9924, Scer\GAL4ap-md544
upd3GD6811, Scer\GAL4NP0001 is a non-suppressor of abnormal cell death | adult stage phenotype of Ets21CUAS.LONG.Tag:MYC, Scer\GAL4NP0001
upd3GD6811, Scer\GAL4NP0001 is a suppressor of intestinal stem cell phenotype of Ets21CUAS.LONG.Tag:MYC, Scer\GAL4NP0001
upd3GD6811, Scer\GAL4NP0001 is a suppressor | partially of adult midgut epithelium phenotype of Ets21CUAS.LONG.Tag:MYC, Scer\GAL4NP0001
upd3GD6811/Scer\GAL4NP0001 is a suppressor of adult midgut epithelium phenotype of Scer\GAL4NP0001, ebd1JF02926
upd3GD6811/Scer\GAL4NP0001 is a suppressor of intestinal stem cell | increased number | adult stage phenotype of Scer\GAL4NP0001, ebd1JF02926
upd3GD6811/Scer\GAL4NP0001 is a suppressor of adult midgut phenotype of Tnks503/Tnks19
upd3GD6811/Scer\GAL4NP0001 is a suppressor of intestinal stem cell | adult stage phenotype of Tnks503/Tnks19
upd3GD6811/Scer\GAL4srp.D.cCa, Scer\GAL80ts.αTub84B is a suppressor | heat sensitive of melanotic mass | heat sensitive phenotype of Scer\GAL4srp.D.cCa, Scer\GAL80ts.αTub84B, gcmDN.UAS
upd3GD6811, Scer\GAL4esg.PU is a non-suppressor of adult midgut epithelium phenotype of Ets21CUAS.LONG.Tag:MYC, Scer\GAL4esg.PU
The increased number of intestinal stem cells in the midgut of adult flies expressing ebd1JF02926 under the control of Scer\GAL4Myo31DF-NP0001 (combined with Gal80[ts] to limit the time of expression to adulthood) can be suppressed by co-expression of upd3GD6811.
The increase in the numbers of intestinal stem cells and mitotic cells present in Tnks19/Tnks503 transheterozygous mutant adult midguts is suppressed by expressing upd3GD6811 under the control of Scer\GAL4Myo31DF-NP0001.
The melanotic tumour phenotype see in animals carrying gcmDN.Scer\UAS.T:en-Rep, Scer\GAL4srp.D.cCa and Scer\GAL80ts.αTub84B which have been raised at 18[o]C and then shifted to 29[o]C during the first larval instar stage is completely suppressed if they are also co-expressing upd3GD6811.