FB2024_03 , released June 25, 2024
Allele: Dmel\Hip1UAS.cMa
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General Information
Symbol
Dmel\Hip1UAS.cMa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Moores
FlyBase ID
FBal0221212
Feature type
allele
Associated gene
Dmel\Hip1
Associated Insertion(s)
Carried in Construct
P{UAS-Hip1.M}
Key Links
Transgenic product class
cDNA
(Moores et al., 2008)
wild_type
(Moores et al., 2008)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Moores et al., 2008)
wild_type
(Moores et al., 2008)
Mutagen
in vitro construct
(Moores et al., 2008)
Progenitor genotype
Carried in construct
P{UAS-Hip1.M}
Cytology
Description

UASt regulatory sequences drive expression of the Hip1 LD30041 cDNA.

(Moores et al., 2008)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Hip1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In

      microchaeta & mesothoracic tergum, with Scer\GAL4ap-md544

      (Moores et al., 2008)

      microchaeta & mesothoracic tergum, with Scer\GAL4pnr-MD237

      (Moores et al., 2008)
      Detailed Description
      Statement
      Reference

      Expression of Hip1Scer\UAS.cMa under the control of either Scer\GAL4ap-md544 or Scer\GAL4pnr-MD237 results in a decrease in density of microchaetae throughout the dorsal notum. There is no effect on gross bristle morphology or on the number or position of macrochaetae.

      (Moores et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      Hip1UAS.cMa, Scer\GAL4pnr-MD237 is an enhancer of visible phenotype of Scer\GAL4pnr-MD237, dxUAS.cMa

      (Moores et al., 2008)
      NOT Enhancer of
      Statement
      Reference

      Hip1UAS.cMa/Scer\GAL4pnr-MD237 is a non-enhancer of visible | dominant phenotype of E(spl)m8-HLH1

      (Moores et al., 2008)
      NOT Suppressor of
      Statement
      Reference

      Hip1UAS.cMa/Scer\GAL4pnr-MD237 is a non-suppressor of visible | dominant phenotype of E(spl)m8-HLH1

      (Moores et al., 2008)
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      Hip1UAS.cMa, Scer\GAL4pnr-MD237 has microchaeta & mesothoracic tergum phenotype, suppressible by ac4

      (Moores et al., 2008)
      Enhancer of
      Statement
      Reference

      Hip1UAS.cMa, Scer\GAL4pnr-MD237 is an enhancer of microchaeta & mesothoracic tergum phenotype of Scer\GAL4pnr-MD237, dxUAS.cMa

      (Moores et al., 2008)

      Hip1UAS.cMa/Scer\GAL4pnr-MD237 is an enhancer of microchaeta & mesothoracic tergum phenotype of NMcd1

      (Moores et al., 2008)
      NOT Enhancer of
      Statement
      Reference

      Hip1UAS.cMa/Scer\GAL4pnr-MD237 is a non-enhancer of microchaeta & mesothoracic tergum phenotype of E(spl)m8-HLH1

      (Moores et al., 2008)
      NOT Suppressor of
      Statement
      Reference

      Hip1UAS.cMa/Scer\GAL4pnr-MD237 is a non-suppressor of microchaeta & mesothoracic tergum phenotype of E(spl)m8-HLH1

      (Moores et al., 2008)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of Hip1Scer\UAS.cMa under the control of Scer\GAL4pnr-MD237 enhances the abnormal microchaetae density phenotype seen on the notum of NMcd1 flies.

      Expression of Hip1Scer\UAS.cMa under the control of Scer\GAL4pnr-MD237 has no effect on the increased density of microchaetae on the notum seen in E(spl)1/+ flies.

      The decreased density of microchaetae on the notum caused by expression of Hip1Scer\UAS.cMa under the control of Scer\GAL4pnr-MD237 is not suppressed by ac4/+ but is suppressed by ac4/Y.

      The phenotype of reduced microchaetae on the notum which is caused by expression of dxScer\UAS.cMa under the control of Scer\GAL4pnr-MD237 at 19[o]C is enhanced by co-expression of Hip1Scer\UAS.cMa, such that microchaetae are almost completely eliminated in the region of Scer\GAL4pnr-MD237 expression.

      (Moores et al., 2008)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Hip1Scer\UAS.cMa
      Hip1UAS.cMa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Moores
      Secondary FlyBase IDs
        References (1)