FB2024_03 , released June 25, 2024
Allele: Dmel\elflessUAS.cCa
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General Information
Symbol
Dmel\elflessUAS.cCa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Caldwell
FlyBase ID
FBal0221269
Feature type
allele
Associated gene
Dmel\elfless
Associated Insertion(s)
Carried in Construct
P{UAS-elfless.C}
Key Links
Transgenic product class
cDNA
(Caldwell et al., 2008)
wild_type
(Caldwell et al., 2008)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Caldwell et al., 2008)
wild_type
(Caldwell et al., 2008)
Mutagen
in vitro construct
(Caldwell et al., 2008)
Progenitor genotype
Carried in construct
P{UAS-elfless.C}
Cytology
Description

UASt regulatory sequences drive expression of the full length elfless AT24563 cDNA.

(Caldwell et al., 2008)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
elfless
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of elflessScer\UAS.cCa under the control of Scer\GAL4GMR.PF results in defects in the eye, including missing or extra interommatidial bristles, pigment loss and deformation of the eye

      (Caldwell et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhanced by
      Statement
      Reference

      Scer\GAL4GMR.PF, elflessUAS.cCa has visible phenotype, enhanceable by effunspecified/eff[+]

      (Caldwell et al., 2008)

      Scer\GAL4GMR.PF, elflessUAS.cCa has abnormal eye color phenotype, enhanceable by effunspecified/eff[+]

      (Caldwell et al., 2008)
      Suppressed by
      Statement
      Reference

      Scer\GAL4GMR.PF, elflessUAS.cCa has abnormal eye color phenotype, suppressible by DroncI24/Nc[+]

      (Caldwell et al., 2008)

      Scer\GAL4GMR.PF, elflessUAS.cCa has visible phenotype, suppressible by DroncI24/Nc[+]

      (Caldwell et al., 2008)
      Phenotype Manifest In
      Enhanced by
      Suppressed by
      Statement
      Reference

      Scer\GAL4GMR.PF, elflessUAS.cCa has pigment cell phenotype, suppressible by DroncI24/Nc[+]

      (Caldwell et al., 2008)

      Scer\GAL4GMR.PF, elflessUAS.cCa has eye phenotype, suppressible by DroncI24/Nc[+]

      (Caldwell et al., 2008)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of elflessScer\UAS.cCa under the control of Scer\GAL4elfless.PC does not rescue the sterility of Df(2L)TW119/Df(2L)TW201 males.

      The severity of the eye defects caused by expression of elflessScer\UAS.cCa under the control of Scer\GAL4GMR.PF is increased if the flies are also heterozygous for effunspecified; the eyes show almost complete pigment loss and severe defects in the interommatidial bristles and in the shape and size of the eye.

      The severity of the eye defects caused by expression of elflessScer\UAS.cCa under the control of Scer\GAL4GMR.PF is decreased if the flies are also heterozygous for NcI24; the eyes show less severe pigmentation and morphological defects.

      (Caldwell et al., 2008)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      elflessScer\UAS.cCa
      elflessUAS.cCa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Caldwell
      Secondary FlyBase IDs
        References (1)