FlyBase Allele Report: Dmel\mys[JF02819]

The expression of mys^JF02819 under the control of Scer\GAL4^BG380, but not Scer\GAL4^how-24B, leads to the neurotransmission across muscle 6 neuromuscular junction exhibiting a significant decrease in mEJP frequency, but not amplitude, as compared to controls.

(Wang et al., 2018)

Adult flies expressing mys^JF02819 under the control of Scer\GAL4^Dot.PK display nephrocyte functional defects (measured by uptake assays) and reduced adult lifespan relative to controls.

(Fu et al., 2017)

Expressing mys^JF02819 under the control of Scer\GAL4^repo (in combination with a Dicer-2 transgene to enhance RNAi efficiency) results in decreased glial cell numbers in the eye discs of third instar larvae. Photoreceptor axon targeting to the optic stalk is unaffected.

(Tavares et al., 2015)

Expression of mys^GD15002 under the control of Scer\GAL4^NP5130, in combination with a Gal80[ts] transgene to restrict expression to the two weeks of adulthood prior to analysis, results in a reduction in Esg-positive progenitors, including a reduction in intestinal stem cell numbers, in the adult posterior midgut, with with a decrease in cell division (PH3 staining) and no increase in apoptosis (TUNEL assay).

(Lin et al., 2013)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Scer\GAL4^NP5130, mys^JF02819 has decreased cell number | adult stage phenotype, non-enhanceable by BacA\p35^UAS.cHa, Scer\GAL4^NP5130

(Lin et al., 2013)

Suppressed by

Statement

Reference

Scer\GAL4^nub.PU, mys^JF02819 has visible | adult stage phenotype, suppressible | partially by Osi17^UAS.cDa, Scer\GAL4^nub.PU

(Dong et al., 2024)

NOT suppressed by

Statement

Reference

Scer\GAL4^NP5130, mys^JF02819 has decreased cell number | adult stage phenotype, non-suppressible by Ras85D^V12.UAS, Scer\GAL4^NP5130

(Lin et al., 2013)

Scer\GAL4^NP5130, mys^JF02819 has decreased cell number | adult stage phenotype, non-suppressible by BacA\p35^UAS.cHa, Scer\GAL4^NP5130

(Lin et al., 2013)

NOT Enhancer of

Statement

Reference

mys^JF02819/Scer\GAL4^repo.PU is a non-enhancer of increased size | larval stage phenotype of Scer\GAL4^repo.PU, kon^{UAS.Tag:HA,Tag:SS(wg)}

(Harrison et al., 2021)

Suppressor of

Statement

Reference

mys^JF02819/Scer\GAL4^Tub.PU is a suppressor of decreased cell size | somatic clone | P-stage phenotype of bark^L200

(Esmangart de Bournonville et al., 2024)

mys^JF02819, Scer\GAL4^elav-C155 is a suppressor of decreased rate of adult locomotory behavior | progressive phenotype of Hsap\HTT^{128Q.1-231.UAS}, Scer\GAL4^elav-C155

(Hernandez et al., 2023)

mys^JF02819, Scer\GAL4^GMR.PU is a suppressor | partially of visible | adult stage phenotype of Hsap\CDH1^R749W.UAS, Scer\GAL4^GMR.PU

(Figueiredo et al., 2022)

mys^JF02819, Scer\GAL4^GMR.PU is a suppressor | partially of increased cell death | adult stage phenotype of Hsap\CDH1^R749W.UAS, Scer\GAL4^GMR.PU

(Figueiredo et al., 2022)

mys^JF02819, Scer\GAL4^GMR.PU is a suppressor | partially of visible | adult stage phenotype of Hsap\CDH1^WT.UAS, Scer\GAL4^GMR.PU

(Figueiredo et al., 2022)

mys^JF02819, Scer\GAL4^GMR.PU is a suppressor | partially of increased cell death | adult stage phenotype of Hsap\CDH1^WT.UAS, Scer\GAL4^GMR.PU

(Figueiredo et al., 2022)

Scer\GAL4^elav.PU/mys^JF02819 is a suppressor of increased size | larval stage phenotype of Scer\GAL4^elav.PU, kon^{UAS.Tag:HA,Tag:SS(wg)}

(Harrison et al., 2021)

mys^JF02819/Scer\GAL4^repo is a suppressor | partially of abnormal neuroanatomy | third instar larval stage phenotype of AdamTS-A^rnwy2/AdamTS-A^rnwy1

(Skeath et al., 2017)

mys^JF02819/Scer\GAL4^Tub.PU is a suppressor | somatic clone of hyperplasia | somatic clone | adult stage phenotype of Apc2^g10, Apc^Q8

(Lin et al., 2013)

NOT Suppressor of

Statement

Reference

mys^JF02819, Scer\GAL4^nub.PU is a non-suppressor of visible | adult stage phenotype of Osi17^GD3626, Scer\GAL4^nub.PU

(Dong et al., 2024)

mys^JF02819/Scer\GAL4^repo.PU is a non-suppressor of increased size | larval stage phenotype of Scer\GAL4^repo.PU, kon^{UAS.Tag:HA,Tag:SS(wg)}

(Harrison et al., 2021)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Scer\GAL4^NP5130, mys^JF02819 has adult posterior midgut epithelium phenotype, non-enhanceable by BacA\p35^UAS.cHa, Scer\GAL4^NP5130

(Lin et al., 2013)

Suppressed by

Statement

Reference

Scer\GAL4^nub.PU, mys^JF02819 has wing phenotype, suppressible | partially by Osi17^UAS.cDa, Scer\GAL4^nub.PU

(Dong et al., 2024)

NOT suppressed by

Statement

Reference

Scer\GAL4^NP5130, mys^JF02819 has adult posterior midgut epithelium phenotype, non-suppressible by Ras85D^V12.UAS, Scer\GAL4^NP5130

(Lin et al., 2013)

Scer\GAL4^NP5130, mys^JF02819 has adult posterior midgut epithelium phenotype, non-suppressible by BacA\p35^UAS.cHa, Scer\GAL4^NP5130

(Lin et al., 2013)

NOT Enhancer of

Statement

Reference

mys^JF02819/Scer\GAL4^repo.PU is a non-enhancer of larval ventral nerve cord phenotype of Scer\GAL4^repo.PU, kon^{UAS.Tag:HA,Tag:SS(wg)}

(Harrison et al., 2021)

Suppressor of

Statement

Reference

mys^JF02819/Scer\GAL4^Tub.PU is a suppressor of cell-cell junction | somatic clone | P-stage phenotype of bark^L200

(Esmangart de Bournonville et al., 2024)

mys^JF02819/Scer\GAL4^Tub.PU is a suppressor of epithelial cell | somatic clone | P-stage phenotype of bark^L200

(Esmangart de Bournonville et al., 2024)

mys^JF02819, Scer\GAL4^GMR.PU is a suppressor | partially of eye phenotype of Hsap\CDH1^R749W.UAS, Scer\GAL4^GMR.PU

(Figueiredo et al., 2022)

mys^JF02819, Scer\GAL4^GMR.PU is a suppressor | partially of eye phenotype of Hsap\CDH1^WT.UAS, Scer\GAL4^GMR.PU

(Figueiredo et al., 2022)

Scer\GAL4^elav.PU/mys^JF02819 is a suppressor of larval ventral nerve cord phenotype of Scer\GAL4^elav.PU, kon^{UAS.Tag:HA,Tag:SS(wg)}

(Harrison et al., 2021)

mys^JF02819/Scer\GAL4^repo is a suppressor | partially of embryonic/larval brain | third instar larval stage phenotype of AdamTS-A^rnwy2/AdamTS-A^rnwy1

(Skeath et al., 2017)

mys^JF02819/Scer\GAL4^Tub.PU is a suppressor | somatic clone of adult posterior midgut epithelium | somatic clone phenotype of Apc2^g10, Apc^Q8

(Lin et al., 2013)

NOT Suppressor of

Statement

Reference

mys^JF02819, Scer\GAL4^nub.PU is a non-suppressor of wing phenotype of Osi17^GD3626, Scer\GAL4^nub.PU

(Dong et al., 2024)

mys^JF02819/Scer\GAL4^repo.PU is a non-suppressor of larval ventral nerve cord phenotype of Scer\GAL4^repo.PU, kon^{UAS.Tag:HA,Tag:SS(wg)}

(Harrison et al., 2021)

Additional Comments

Genetic Interactions

Statement

Reference

The neural invasion phenotype (neural cells from the brain invade adjacent peripheral structures such as imaginal discs) observed in AdamTS-A^rnwy1/AdamTS-A^rnwy2 mutant third instar larvae is partially suppressed by Scer\GAL4^repo-driven expression of mys^JF02819.

(Skeath et al., 2017)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

27735

y¹ v¹; P{TRiP.JF02819}attP2/TM3, Sb¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

mys^JF02819

Name Synonyms

Secondary FlyBase IDs

References (20)

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