FB2024_03 , released June 25, 2024
Allele: Dmel\mod(mdg4)ΔQ.UAS
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General Information
Symbol
Dmel\mod(mdg4)ΔQ.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0243879
Feature type
allele
Associated gene
Dmel\mod(mdg4)
Associated Insertion(s)
Carried in Construct
P{UAS-mod(mdg4).ΔQ}
Key Links
Transgenic product class
inframe_deletion
(Golovnin et al., 2008)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Golovnin et al., 2008)
Mutagen
in vitro construct
(Golovnin et al., 2008)
Progenitor genotype
Carried in construct
P{UAS-mod(mdg4).ΔQ}
Cytology
Description

UAS regulatory sequences drive expression of a truncated form of mod(mdg4), carrying a deletion which removes the glutamine (Q)-rich domain and one NLS (residues 145-276).

(Golovnin et al., 2008)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
mod(mdg4)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4Act5C.PU/mod(mdg4)ΔQ.UAS rescues mod(mdg4)ul

      (Golovnin et al., 2008)
      Comments

      Expression of mod(mdg4)ΔQ.Scer\UAS under the control of Scer\GAL4Act5C in a y2 mutant background completely overrides the y2,mod(mdg4)ul phenotype, resulting in flies that have a y2 appearance, with a paler abdomen and dark bristles.

      Expression of mod(mdg4)ΔQ.Scer\UAS under the control of Scer\GAL4Act5C in a ct6,mod(mdg4)ul mutant background suppresses the effect that mod(mdg4)ul has on ct6 wings, and the wings that form lack the wing margin and are similar to ct6 wings.

      Expression of mod(mdg4)ΔQ.Scer\UAS under the control of Scer\GAL4Act5C in a ctK,mod(mdg4)ul mutant background suppresses the effect that mod(mdg4)ul has on ctK wings, and the wings that form lack regions of the wing margin and are similar to ctK wings.

      (Golovnin et al., 2008)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      mod(mdg4)ΔQ.Scer\UAS
      mod(mdg4)ΔQ.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (3)