FB2024_03 , released June 25, 2024
Allele: Dmel\scUAS.cUa
Open Close
General Information
Symbol
Dmel\scUAS.cUa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Unknown
FlyBase ID
FBal0244020
Feature type
allele
Associated gene
Dmel\sc
Associated Insertion(s)
Carried in Construct
P{UAS-sc.U}
Also Known As
UAS-sc
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Ayyar et al., 2007)
Progenitor genotype
Carried in construct
P{UAS-sc.U}
Cytology
Description

UAS regulatory sequences drive expression of sc.

(Ayyar et al., 2007)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
sc
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of scUAS.cUa under the control of Scer\GAL4pnr-MD237 leads to ectopic dorsocentral macrochaetae in notum when compared to control adults.

      (Liang et al., 2018)

      Expression of scScer\UAS.cUa under the control of Scer\GAL4Dl-05151-G in adult midguts leads to a significant increase in the number of enteroendocrine cells, and an increase in the number of dividing cells per gut, as compared to controls.

      (Li et al., 2017)

      Expression of scScer\UAS.cUa under the control of Scer\GAL4DC results in additional dorsocentral bristles (approximately 28% of flies have more than two dorsocentral bristles per hemithorax).

      (Yang et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of esgScer\UAS.cFa suppresses the increased enteroendocrine cell number and the dividing cell number in adult midguts expressing scScer\UAS.cUa under the control of Scer\GAL4Dl-05151-G.

      (Li et al., 2017)

      Expression of scSA.Scer\UAS under the control of Scer\GAL4DC results in greater rescue of the loss of dorsocentral bristles seen in wgSp-1/wgl-17 flies than expression of scScer\UAS.cUa under the control of Scer\GAL4DC.

      (Yang et al., 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      scUAS.cUa/Scer\GAL4hs.PB fails to rescue scase-1

      (Ayyar et al., 2010)
      Comments

      Expression of scScer\UAS.cUa under the control of Scer\GAL4hs.PB fails to rescue the mechanosensory bristle defects found in scase-1 mutants.

      (Ayyar et al., 2010)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      scScer\UAS.cUa
      scUAS.cUa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Unknown
      Secondary FlyBase IDs
        References (9)