FB2024_03 , released June 25, 2024
Allele: Dmel\gcmJF01075
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General Information
Symbol
Dmel\gcmJF01075
Species
D. melanogaster
Name
FlyBase ID
FBal0245397
Feature type
allele
Associated gene
Dmel\gcm
Associated Insertion(s)
Carried in Construct
P{TRiP.JF01075}
Also Known As
UAS-gcmRNAi, UASgcmRNAi
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Ni et al., 2008)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Ni et al., 2008)
Mutagen
in vitro construct
(Ni et al., 2008)
Progenitor genotype
Carried in construct
P{TRiP.JF01075}
Cytology
Description

UAS regulatory sequences drive expression of an inverted repeat.

(Ni et al., 2008)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
dsRNA-JF01075
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The expression of gcmJF01075 under the control of either Scer\GAL4lz-gal4 or Scer\GAL4gcm-rA87.P, the intrinsic Gal4 from the gcmrA87.P allele, results in a significant decrease in the number of secretory cells in adult spermatheca, but in no obvious defect in lumen epithelial cells, as compared to controls.

      (Cattenoz et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressed by
      Enhancer of
      NOT Enhancer of
      Statement
      Reference

      gcmJF01075/Scer\GAL4gcm-rA87.P is a non-enhancer of lamellocyte | larval stage | increased number phenotype of Tl10b

      (Bazzi et al., 2023)
      NOT Suppressor of
      Statement
      Reference

      gcmJF01075/Scer\GAL4gcm-rA87.P is a non-suppressor of lamellocyte | increased number | larval stage phenotype of Tl10b

      (Bazzi et al., 2023)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expressing Hr39Scer\UAS.ORF.GW.T:Ivir\HA1 partially suppresses the decreased number of spermathecae secretory cells resulting from the expression of gcmJF01075 under the control of Scer\GAL4lz-gal4.

      (Cattenoz et al., 2016)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      gcmJF01075 is rescued by gcmUAS.cBa/Scer\GAL4gcm-rA87.P

      (Cattenoz et al., 2016)
      Comments

      The expression of gcmScer\UAS.cBa under the control of Scer\GAL4gcm-rA87.P, the intrinsic Gal4 from the gcmrA87.P allele, rescues the decreased number of secretory cells in spermathecae expressing gcmJF01075 also under the control of Scer\GAL4gcm-rA87.P, even leading to their significant increase in number as compared to controls.

      (Cattenoz et al., 2016)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      gcmJF01075
      Name Synonyms
      Secondary FlyBase IDs
        References (5)