FB2024_03 , released June 25, 2024
Allele: Dmel\Mdh2UAS.cWa
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General Information
Symbol
Dmel\Mdh2UAS.cWa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Wang
FlyBase ID
FBal0246554
Feature type
allele
Associated gene
Dmel\Mdh2
Associated Insertion(s)
Carried in Construct
P{UAS-Mdh2.W}
Key Links
Transgenic product class
cDNA
(Wang et al., 2010)
wild_type
(Wang et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Wang et al., 2010)
wild_type
(Wang et al., 2010)
Mutagen
in vitro construct
(Wang et al., 2010)
Progenitor genotype
Carried in construct
P{UAS-Mdh2.W}
Cytology
Description

UASt drives expression of the RE60471 full-length cDNA.

(Wang et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Mdh2
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Suppressor of
      Statement
      Reference

      Scer\GAL4Act5C.PU/Mdh2UAS.cWa is a non-suppressor of lethal | pupal stage phenotype of MED241

      (Wang et al., 2010)
      Phenotype Manifest In
      NOT Suppressor of
      Statement
      Reference

      Scer\GAL4Act5C.PU/Mdh2UAS.cWa is a non-suppressor of embryonic/larval salivary gland | pupal stage phenotype of MED241

      (Wang et al., 2010)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Scer\GAL4Act5C.PU-mediated expression of Mdh2Scer\UAS.cWa fails to restore normal salivary gland cell death or rescue pupal lethality of MED241 animals.

      (Wang et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Mdh2UAS.cWa rescues Mdh21/Df(3R)Exel6178

      (Wang et al., 2010)
      Comments

      Scer\GAL4Act5C.PU-mediated expression of Mdh2Scer\UAS.cWa restores normal salivary gland cell death and efficiently rescues pupal lethality in Mdh21/Df(3R)Exel6178 animals.

      (Wang et al., 2010)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Mdh2Scer\UAS.cWa
      Mdh2UAS.cWa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Wang
      Secondary FlyBase IDs
        References (1)