FB2024_03 , released June 25, 2024
Allele: Dmel\Ir84aUAS.Tag:SS(hCALR),EGFP
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General Information
Symbol
Dmel\Ir84aUAS.Tag:SS(hCALR),EGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0249367
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-EGFP:IR84a
Key Links
Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

UAS regulatory sequences drive expression of wild-type Ir84a with the endogenous signal sequence replaced with Tag:SS(hCALR) and fused to EGFP.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Neurons expressing Ir84aScer\UAS.T:Hsap\CALR,T:Avic\GFP-EGFP driven by Scer\GAL4Or22a.7.717 do not respond to phenylacetaldehyde above basal solvent-evoked activity.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Neurons co-expressing Ir84aScer\UAS.T:Hsap\CALR,T:Avic\GFP-EGFP and Ir8aScer\UAS.T:Hsap\CALR,T:Avic\GFP-EGFP under the control of Scer\GAL4Or22a.7.717 respond to phenylacetaldehyde in a concentration-dependent manner.

Neurons co-expressing Ir84aScer\UAS.T:Hsap\CALR,T:Avic\GFP-EGFP and Ir8aScer\UAS.T:Hsap\CALR,T:Disc\RFP-mCherry under the control of Scer\GAL4Or22a.7.717 respond to phenylacetaldehyde in a concentration-dependent manner.

Neurons co-expressing Ir84aScer\UAS.T:Hsap\CALR,T:Avic\GFP-EGFP and Ir8aScer\UAS.cAa under the control of Scer\GAL4Or22a.7.717 respond to phenylacetaldehyde in a concentration-dependent manner.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

Expression of Ir84aScer\UAS.T:Hsap\CALR,T:Avic\GFP-EGFP using Scer\GAL4Ir84a-GAL4 restores the response to phenylacetic acid and phenylacetaldehyde in Ir84aGAL4 homozygotes.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Ir84aScer\UAS.T:Hsap\CALR,T:Avic\GFP-EGFP
Ir84aScer\UAS.T:Hsap\SS-CALR,T:Avic\GFP-EGFP
Ir84aUAS.Tag:SS(hCALR),EGFP
Name Synonyms
Secondary FlyBase IDs
    References (3)