FB2024_03 , released June 25, 2024
Allele: Dmel\StamHMS01429
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General Information
Symbol
Dmel\StamHMS01429
Species
D. melanogaster
Name
FlyBase ID
FBal0263338
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
HMS01429
Key Links
Genomic Maps

Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

UAS regulatory sequences drive expression of a short inverted repeat.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of StamHMS01429 RNAi under the control of Scer\GAL4Act.PU in somatic clones induced specifically in the eye results in moderately reduced adult eye size compared to controls.

Embryos derived from females expressing StamHMS01429 under the simultaneous control of Scer\GAL4otu.T:Hsim\VP16, Scer\GAL4nos.PG and Scer\GAL4nos.UTR.T:Hsim\VP16 show a significant delay in the clearance of the paternal mitochondrial derivatives compared to wild type.

Females heterozygous for StamHMS01429 and MTD-Gal4 (consists of Scer\GAL4otu.T:Hsim\VP16, Scer\GAL4nos.PG and Scer\GAL4nos.UTR.T:Hsim\VP16) crossed to StamHMS01429 males results in: 78% hatching; non-maternal effect.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Phenotype Manifest In
Enhancer of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

The smaller adult eye size characteristic for animals expressing RbfHMS03004 RNAi under the control of the Scer\GAL4Act.PU driver in somatic clones induced specifically in the eye can be reduced further by co-expression of StamHMS01429 RNAi.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
StamHMS01429
Name Synonyms
Secondary FlyBase IDs
    References (7)