FB2024_03 , released June 25, 2024
Allele: Dmel\etUAS.cMa
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General Information
Symbol
Dmel\etUAS.cMa
Species
D. melanogaster
Name
FlyBase ID
FBal0264424
Feature type
allele
Associated gene
Dmel\et
Associated Insertion(s)
Carried in Construct
P{UAS-et.M}
Also Known As
UAS-lat, UAS-Latran
Key Links
Transgenic product class
wild_type
(Makki et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Makki et al., 2010)
Mutagen
in vitro construct
(Makki et al., 2010)
Progenitor genotype
Carried in construct
P{UAS-et.M}
Cytology
Description

et coding sequences are fused downstream of UAS regulatory sequences.

(Makki et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
et
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      etScer\UAS.cMa overexpression under the control of Scer\GAL4dome-PG125 leads to a complete inhibition of JAK/STAT signalling in the medullary cells while both crystal cells and plasmatocytes are still able to differentiate.

      Scer\GAL4dome-PG125-driven expression of two copies of etScer\UAS.cMa results in early larval lethality.

      Expression of etScer\UAS.cMa under the control of Scer\GAL4dome-PG125 results in an 'outstretched wing' phenotype in adult flies.

      Expression of etScer\UAS.cMa in the developing eye under the control of Scer\GAL4ey.PH leads to smaller eyes.

      (Makki et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      etUAS.cMa/Scer\GAL4srp.D.cCa rescues et18A

      (Makki et al., 2010)
      Comments

      Expression of etScer\UAS.cMa under the control of Scer\GAL4srp.D.cCa restores the ability of et18A mutant larvae to produce lamellocytes following wasp parasitisation.

      (Makki et al., 2010)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      etScer\UAS.cMa
      etUAS.cMa
      Name Synonyms
      Secondary FlyBase IDs
        References (3)