FB2024_03 , released June 25, 2024
Allele: Dmel\dl25.Venus
Open Close
General Information
Symbol
Dmel\dl25.Venus
Species
D. melanogaster
Name
FlyBase ID
FBal0269190
Feature type
allele
Associated gene
Dmel\dl
Associated Insertion(s)
Carried in Construct
M{dl-Venus.25}
Also Known As
dl-venus
Key Links
Transgenic product class
genomic_DNA
(Reeves et al., 2012)
wild_type
(Reeves et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Reeves et al., 2012)
wild_type
(Reeves et al., 2012)
Mutagen
in vitro construct
(Reeves et al., 2012)
Progenitor genotype
Carried in construct
M{dl-Venus.25}
Cytology
Description

25kb genomic fragment which contains the dl locus derived from the BACR07M13 clone. A Venus tag has been inserted at the C-terminal end of the dl open reading frame, with a 6XGly linker added before the start of the tag.

(Reeves et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
dl
Encoded product / tool
dl
Tagged with
Venus
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter or direct label
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic cycle 11 -- embryonic cycle 14
      organism | ventral

      Comment: live-imaging

      (Reeves et al., 2012)
      Additional Information
      Statement
      Reference

      The percentage of dl25.Venus intensity (as visualized by two-photon scanned light-sheet microscopy) localized to the nucleus increases during each nuclear cycle from embryonic cycles 11 to 14, then falls at the end of the cycle. This pattern can be explained by the nuclei filling with Dorsal-Venus relatively slowly throughout each nuclear cycle interphase, then rapidly equilibrating with the cytoplasm when the nuclear envelopes break down at the beginning of mitosis.

      (Reeves et al., 2012)
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      dl25.T:Avic\GFP-YFP.Venus
      dl25.Venus
      Name Synonyms
      Secondary FlyBase IDs
        References (3)