FB2024_03 , released June 25, 2024
Allele: Dmel\Diap2BIR23mut.UAS
Open Close
General Information
Symbol
Dmel\Diap2BIR23mut.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0270259
Feature type
allele
Associated gene
Dmel\Diap2
Associated Insertion(s)
Carried in Construct
M{UAS-Diap2.BIR23mut}
Key Links
Transgenic product class
missense_variant
(Meinander et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Meinander et al., 2012)
Mutagen
in vitro construct
(Meinander et al., 2012)
Progenitor genotype
Carried in construct
M{UAS-Diap2.BIR23mut}
Cytology
Description

UASt regulatory sequences drive expression of Diap2 containing a mutation in the BIR2 and BIR3 domains (amino acid replacements D163A and D263A).

(Meinander et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Diap2
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      Scer\GAL4c564/Diap2BIR23mut.UAS fails to rescue Diap27c

      (Meinander et al., 2012)
      Comments

      Expression of Iap2BIR23mut.Scer\UAS under the control of Scer\GAL4da.G32 fails to rescue the reduced survival after septic injury with Erwinia carotovora carotovora 15 which is seen in Iap27c flies.

      (Meinander et al., 2012)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      DIAP2BIR2/3mut
      (Meinander et al., 2012)
      Diap2BIR23mut.Scer\UAS
      Diap2BIR23mut.UAS
      Iap2BIR23mut.Scer\UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)