FB2024_03 , released June 25, 2024
Allele: Dmel\hpoM242E.UAS.Tag:FLAG
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General Information
Symbol
Dmel\hpoM242E.UAS.Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0279496
Feature type
allele
Associated gene
Dmel\hpo
Associated Insertion(s)
Carried in Construct
P{UAS-hpo.M242E.FLAG}
Key Links
Transgenic product class
missense_variant
(Jin et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Jin et al., 2012)
Mutagen
in vitro construct
(Jin et al., 2012)
Progenitor genotype
Carried in construct
P{UAS-hpo.M242E.FLAG}
Cytology
Description

UAS regulatory sequences drive expression of a mutated form of hpo containing the amino acid replacement M242E. The protein is tagged with Tag:FLAG.

(Jin et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
hpo
Tagged with
Tag:FLAG
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of hpoM242E.Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4Bx-MS1096 results in a slight increase in wing size compared to controls.

      (Jin et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      hpoM242E.UAS.Tag:FLAG/Scer\GAL4GMR.PU is an enhancer of visible phenotype of Scer\GAL4GMR.PU, ykiUAS.cZa

      (Jin et al., 2012)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      hpoM242E.UAS.Tag:FLAG/Scer\GAL4GMR.PU is an enhancer of eye phenotype of Scer\GAL4GMR.PU, ykiUAS.cZa

      (Jin et al., 2012)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of hpoM242E.Scer\UAS.T:Zzzz\FLAG enhances the eye overgrowth phenotype caused by expression of ykiScer\UAS.cZa under the control of Scer\GAL4GMR.PU.

      (Jin et al., 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4Tub.PU/hpoM242E.UAS.Tag:FLAG partially rescues hpoBF33

      (Jin et al., 2012)
      Comments

      Expression of hpoM242E.Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4tub.PU partially rescues the overgrowth phenotype caused by hpoBF33 clones in the eye.

      (Jin et al., 2012)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      hpoM242E.Scer\UAS.T:Zzzz\FLAG
      hpoM242E.UAS.Tag:FLAG
      Name Synonyms
      Secondary FlyBase IDs
        References (1)