FB2024_03 , released June 25, 2024
Allele: Dmel\IdeUAS.cGa
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General Information
Symbol
Dmel\IdeUAS.cGa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Galagovsky
FlyBase ID
FBal0296607
Feature type
allele
Associated gene
Dmel\Ide
Associated Insertion(s)
Carried in Construct
P{UAS-Ide.G}
Key Links
Transgenic product class
cDNA
(Galagovsky et al., 2014)
wild_type
(Galagovsky et al., 2014)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Galagovsky et al., 2014)
wild_type
(Galagovsky et al., 2014)
Mutagen
in vitro construct
(Galagovsky et al., 2014)
Progenitor genotype
Carried in construct
P{UAS-Ide.G}
Cytology
Description

UAS regulates expression of the Ide ORF from EST clone RE17458.

(Galagovsky et al., 2014)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Ide
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Scer\GAL4Act5C.PI-mediated expression of IdeScer\UAS.cGa results in a 12.3% reduction of pupal volume in comparison to controls.

      Scer\GAL4Bx-MS1096-KE-mediated expression of IdeScer\UAS.cGa results in wings that are curved upward, indicating that expression restricts growth in a cell-autonomous manner.

      Scer\GAL4en-e16E-mediated expression of IdeScer\UAS.cGa results in wings with a 19.1% reduction of the region bordered by the 4th and 5th wing veins, the posterior cross vein and the wing margin, indicating that expression restricts growth in a cell-autonomous manner. This reduction in size is the result of reduced cell size and reduced cell number.

      Scer\GAL4ptc-559.1-mediated expression of IdeScer\UAS.cGa results in wings with a reduction of the region of expression, indicating that expression restricts growth in a cell-autonomous manner. This reduction in size is the result of reduced cell size and reduced cell number.

      (Galagovsky et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      IdeUAS.cGa, Scer\GAL4Bx-MS1096-KE has wing phenotype, suppressible | partially by Pten117/Pten[+]

      (Galagovsky et al., 2014)

      IdeUAS.cGa, Scer\GAL4en-e16E has wing phenotype, suppressible | partially by Pten117/Pten[+]

      (Galagovsky et al., 2014)

      IdeUAS.cGa, Scer\GAL4Bx-MS1096-KE has wing phenotype, suppressible | partially by foxo21/foxo[+]

      (Galagovsky et al., 2014)

      IdeUAS.cGa, Scer\GAL4en-e16E has wing phenotype, suppressible | partially by foxo21/foxo[+]

      (Galagovsky et al., 2014)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      IdeScer\UAS.cGa
      IdeUAS.cGa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Galagovsky
      Secondary FlyBase IDs
        References (1)