FlyBase Allele Report: Dmel\eya[cs]

General Information

Symbol

Dmel\eya^cs

Species

D. melanogaster

Name

FlyBase ID

FBal0357069

Feature type

allele

Associated gene

Dmel\eya

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

115bp deletion approximately 700bp upstream of the Exon 1B promoter.

(Tian et al., 2019)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

deletion

2L:6,547,667..6,547,782 [-]

Comment:

eya^cs is a deletion that maps from -806 to -691 relative to the eya-RB TSS.

(Tian et al., 2019)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal size | adult stage

(Tian et al., 2019)

abnormal size | adult stage (with eya¹)

(Tian et al., 2019)

abnormal size | adult stage (with eya³)

(Tian et al., 2019)

abnormal size | adult stage (with eya⁴)

(Tian et al., 2019)

abnormal size | adult stage (with eya^cli-IID)

(Tian et al., 2019)

abnormal size | adult stage (with eya^E4)

(Tian et al., 2019)

abnormal size | adult stage (with eya^E(P)10)

(Tian et al., 2019)

abnormal size | adult stage (with In(2LR)ETD2.2)

(Tian et al., 2019)

abnormal size | adult stage (with T(2;3;4)ETD4.3)

(Tian et al., 2019)

viable

(Tian et al., 2019)

visible | adult stage

(Tian et al., 2019)

visible | adult stage (with eya¹)

(Tian et al., 2019)

visible | adult stage (with eya²)

(Tian et al., 2019)

visible | adult stage (with eya³)

(Tian et al., 2019)

visible | adult stage (with eya⁴)

(Tian et al., 2019)

visible | adult stage (with eya^cli-IID)

(Tian et al., 2019)

visible | adult stage (with eya^E4)

(Tian et al., 2019)

visible | adult stage (with eya^E(P)10)

(Tian et al., 2019)

visible | adult stage (with In(2LR)ETD2.2)

(Tian et al., 2019)

visible | adult stage (with T(2;3;4)ETD4.3)

(Tian et al., 2019)

Phenotype Manifest In

eye

(Tian et al., 2019)

eye (with eya¹)

(Tian et al., 2019)

eye (with eya²)

(Tian et al., 2019)

eye (with eya³)

(Tian et al., 2019)

eye (with eya⁴)

(Tian et al., 2019)

eye (with eya^cli-IID)

(Tian et al., 2019)

eye (with eya^E4)

(Tian et al., 2019)

eye (with eya^E(P)10)

(Tian et al., 2019)

eye (with In(2LR)ETD2.2)

(Tian et al., 2019)

eye (with T(2;3;4)ETD4.3)

(Tian et al., 2019)

Detailed Description

Statement

Reference

Almost all of eya²/eya^cs adults and some of eya¹/eya^cs are eyeless.

eya^cs/eya³ and eya^cs/eya⁴ adults exhibit greater number of ommatidia than eya^cs/eya^cs, eya^cs/eya^cli-IID, eya^cs/eya^E4 and eya^cs/T(2;3;4)ETD4.3 adults.

Adults bearing following genotypes exhibit eye phenotypes in the descending order of severity: eya^cs/eya² (most severe), eya^cs/eya¹, eya^cs/In(2LR)ETD2.2, eya^cs/eya^cs and eya^cs/eya^E(P)10 (least severe).

(Tian et al., 2019)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

eya^cs/eya¹ has visible | adult stage phenotype, enhanceable by Pc¹/Pc[+]

(Tian et al., 2019)

eya^cs/eya² has visible | adult stage phenotype, enhanceable by Pc¹/Pc[+]

(Tian et al., 2019)

Suppressed by

Statement

Reference

eya^cs/eya¹ has visible | adult stage phenotype, suppressible | partially by E(z)[+]/E(z)⁶⁰

(Tian et al., 2019)

eya^cs/eya¹ has abnormal size | adult stage phenotype, suppressible | partially by E(z)[+]/E(z)⁶⁰

(Tian et al., 2019)

eya^cs/eya¹ has visible | adult stage phenotype, suppressible | partially by Pc[+]/Pc⁴

(Tian et al., 2019)

eya^cs/eya¹ has abnormal size | adult stage phenotype, suppressible | partially by Pc[+]/Pc⁴

(Tian et al., 2019)

eya^cs/eya² has visible | adult stage phenotype, suppressible | partially by E(z)[+]/E(z)⁶⁰

(Tian et al., 2019)

Phenotype Manifest In

Enhanced by

Statement

Reference

eya^cs/eya¹ has eye phenotype, enhanceable by Pc¹/Pc[+]

(Tian et al., 2019)

eya^cs/eya² has eye phenotype, enhanceable by Pc¹/Pc[+]

(Tian et al., 2019)

Suppressed by

Statement

Reference

eya^cs/eya¹ has eye phenotype, suppressible | partially by E(z)[+]/E(z)⁶⁰

(Tian et al., 2019)

eya^cs/eya¹ has eye phenotype, suppressible | partially by Pc[+]/Pc⁴

(Tian et al., 2019)

eya^cs/eya² has eye phenotype, suppressible | partially by E(z)[+]/E(z)⁶⁰

(Tian et al., 2019)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Partially complements

eya^cli-IID

(Tian et al., 2019)

eya^E4

(Tian et al., 2019)

eya⁴

(Tian et al., 2019)

eya³

(Tian et al., 2019)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

eya^cs

(Tian et al., 2019)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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