131bp deletion followed by a 1bp insertion; the entire mir-210 stem loop is removed.
mir-210Δ130 homozygotes exhibit retina degeneration, with the progressive defects in photoreceptor morphology and number and rhabdomere morphology and number; there is accumulation of lipid droplets in the retina. The size of rhabdomere appears slightly smaller at 48h after pupariation (APF), and there is a mild defect in the morphology and organization of rhabdomeres at 96h APF.
mir-210Δ130 has decreased cell number | adult stage | progressive phenotype, suppressible by SREBP[+]/SREBP189
mir-210Δ130 has decreased cell number | adult stage | progressive phenotype, suppressible | partially by Scer\GAL4ninaE.PT/AcCoASVSH330367
mir-210Δ130 has decreased cell number | adult stage | progressive phenotype, suppressible | partially by AcCoASCB-6224-3/AcCoAS[+]
mir-210Δ130 has eye photoreceptor cell | adult stage | decreased number phenotype, suppressible | partially by Scer\GAL4ninaE.PT/AcCoASVSH330367
mir-210Δ130 has rhabdomere | adult stage | decreased number phenotype, suppressible | partially by Scer\GAL4ninaE.PT/AcCoASVSH330367
mir-210Δ130 has eye photoreceptor cell | adult stage | decreased number phenotype, suppressible | partially by AcCoASCB-6224-3/AcCoAS[+]
mir-210Δ130 has retina | adult stage phenotype, suppressible | partially by AcCoASCB-6224-3/AcCoAS[+]
mir-210Δ130 has rhabdomere | adult stage | decreased number phenotype, suppressible | partially by AcCoASCB-6224-3/AcCoAS[+]
mir-210Δ130 has retina | adult stage phenotype, suppressible by SREBP[+]/SREBP189
mir-210Δ130 has lipid droplet | increased number | adult stage phenotype, suppressible by SREBP[+]/SREBP189
mir-210Δ130 has rhabdomere | adult stage | decreased number phenotype, suppressible by SREBP[+]/SREBP189
mir-210Δ130 has eye photoreceptor cell | adult stage | decreased number phenotype, suppressible by SREBP[+]/SREBP189
mir-210Δ130 has retina | adult stage phenotype, suppressible | partially by Scer\GAL4ninaE.PT/AcCoASVSH330367
mir-210Δ130 has lipid droplet | increased number | adult stage phenotype, non-suppressible by Scer\GAL4ninaE.PT/AcCoASVSH330367
mir-210Δ130 has lipid droplet | increased number | adult stage phenotype, non-suppressible by AcCoASCB-6224-3/AcCoAS[+]
mir-210Δ130 is rescued by mir-210+t2.5