TSN
Please see the JBrowse view of Dmel\Tudor-SN for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.45
The group(s) of polypeptides indicated below share identical sequence to each other.
Associates with the RNA-induced silencing complex (RISC) (PubMed:14508492). Interacts with the RISC components AGO2, Fmr1 and vig (PubMed:14508492). Interacts with piwi (PubMed:26808625).
Tudor domain specifically binds peptides with symmetrically dimethylated arginines (sDMA) and may facilitate protein-protein interactions.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Tudor-SN using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Comment: maternally deposited
Tudor-SN protein is detected throughout development on western blots with the highest levels in embryos, ovary, and testis. It localizes to the cytoplasm of both germline and somatic cells in the germarium and developing egg chambers. It is also found in the cytoplasm of germline and somatic cells in the testis.
Comment: expression throughout adult brain
JBrowse - Visual display of RNA-Seq signals
View Dmel\Tudor-SN in JBrowse3-1
3-0.0
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Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
polyclonal
snoRNA:Tudor-SN-a is encoded in an intron of Tudor-SN.
Source for identity of: Tudor-SN CG7008