CAF1
Please see the JBrowse view of Dmel\Pop2 for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.45
Gene model reviewed during 5.55
Low-frequency RNA-Seq exon junction(s) not annotated.
Stop-codon suppression (UGA) postulated; FBrf0243886.
Gene model reviewed during 6.33
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Pop2 using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Comment: maternally deposited
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Expression is observed in all cells of the ovary at all stages of oogenesis.
JBrowse - Visual display of RNA-Seq signals
View Dmel\Pop2 in JBrowse3-38
3-30.4
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
dsRNA made from templates generated with primers directed against this gene are used to study its function.
dsRNA has been made from templates generated with primers directed against this gene. RNAi of Pop2 causes dorsal overextension of the primary dendrite in ddaE and an overall increase in dendritic length in both ddaD and ddaE neurons. RNAi also causes defects in muscle and defects in dendrite morphogenesis.
Depletion of Pop2 using dsRNA interference (RNAi) in S2 cells results in a strong increase in the average mRNA poly(A) length.
Source for identity of: CG5684 Pop2