FlyBase Gene Report: Dmel\Tango1

General Information

Symbol

Dmel\Tango1

Species

D. melanogaster

Name

Transport and Golgi organization 1

Annotation Symbol

CG11098

Feature Type

protein_coding_gene

FlyBase ID

FBgn0286898

Gene Model Status

Current

Stock Availability

14 publicly available

Gene Summary

Transport and Golgi organization 1 (Tango1) is the only Drosophila member of the MIA/cTAGE (melanoma inhibitory activity/cutaneous T cell lymphoma-associated antigen) gene family. It encodes a transmembrane protein required for correct ER exit site (ERES) morphogenesis and general secretion. The Tango1 product maintains ERES size and ERES-Golgi connection through self-interaction and interactions with Sec23, Rab1 and cis-Golgi proteins. [Date last reviewed: 2021-11-04] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
UniProtKB
Interactive Fly

Key Links

Genomic Location

Cytogenetic map

26F3-26F5

Sequence location

2L:6,649,388..6,654,574 [+]

Recombination map

2-21

RefSeq locus

NT_033779 REGION:6649388..6654574

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (12 terms)

Molecular Function (2 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

enables protein-folding chaperone binding

inferred from electronic annotation with InterPro:IPR036533

(InterPro Project Members, 2004-)

Biological Process (6 terms)

Terms Based on Experimental Evidence (4 terms)

CV Term

Evidence

References

involved_in Golgi organization

inferred from mutant phenotype

(Bard et al., 2006)

involved_in positive regulation of secretion

inferred from mutant phenotype

(Zhang et al., 2014)

involved_in protein secretion

inferred from mutant phenotype

(Bard et al., 2006)

involved_in secretory granule organization

inferred from mutant phenotype

(Zhang et al., 2014)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

involved_in endoplasmic reticulum to Golgi vesicle-mediated transport

inferred from biological aspect of ancestor with PANTHER:PTN000570072

(GO Reference Genome Project, 2011-)

involved_in protein secretion

inferred from biological aspect of ancestor with PANTHER:PTN000570072

(GO Reference Genome Project, 2011-)

involved_in vesicle cargo loading

inferred from biological aspect of ancestor with PANTHER:PTN000570072

(GO Reference Genome Project, 2011-)

Cellular Component (5 terms)

Terms Based on Experimental Evidence (4 terms)

CV Term

Evidence

References

located_in endomembrane system

inferred from high throughput direct assay

(Tan et al., 2009)

located_in endoplasmic reticulum exit site

inferred from direct assay

(Lerner et al., 2013, Wendler et al., 2010)

located_in Golgi apparatus

inferred from direct assay

(Bard et al., 2006)

located_in Golgi cis cisterna

inferred from direct assay

(Lerner et al., 2013)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

is_active_in endoplasmic reticulum exit site

inferred from biological aspect of ancestor with PANTHER:PTN000570072

(GO Reference Genome Project, 2011-)

is_active_in endoplasmic reticulum membrane

inferred from biological aspect of ancestor with PANTHER:PTN000570072

(GO Reference Genome Project, 2011-)

Gene Group (FlyBase)

Protein Family (UniProt)

Belongs to the MIA/OTOR family. Tango1 subfamily. (Q9VMA7)

Protein Signatures (InterPro)

Summaries

Gene Snapshot

Protein Function (UniProtKB)

Required for protein secretion (PubMed:16452979, PubMed:23369713). May participate in cargo loading by binding to COPII coat subunits and guiding SH3-bound proteins into a growing carrier (PubMed:16452979). At basal transitional ER sites in follicle epithelial cells, mediates the exit of basal membrane protein such as vkg, LanB1 and Trol, from the endoplasmic reticulum (ER) to basal Golgi clusters (PubMed:23369713).

(UniProt, Q9VMA7)

Summary (Interactive Fly)

transmembrane protein of the ER - plays a general role in secretion at endoplasmic reticulum exit sites, transfer of proteins from the ER to the Golgi - salivary glands - trachea - secretion of collagen from fat body - laminin secretion in glia - forms ring-like structures that mediate the formation of COPII rings that act as docking sites for the cis-Golgi

Interactive Fly

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\Tango1 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry Q9VMA7)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Gene model reviewed during 5.44

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.52

Sequence Ontology: Class of Gene

gene

(Baer et al., 2007)

nuclear_gene

protein_coding_gene

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

Tango1-RA

FBtr0079295

NM_135214

4679

1430

Tango1-RC

FBtr0303224

NM_164697

4521

1430

Tango1-RD

FBtr0343864

NM_001298755

4661

1424

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

Tango1-PA

FBpp0078925

159.1

1430

4.37

FBpp0292316

159.1

1430

4.37

FBpp0310403

158.4

1424

4.37

X2J786

NP_001285684

AHN54199

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

1430 aa isoforms: Tango1-PA, Tango1-PC

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Tango1 using the Feature Mapper tool.

External Data

Crossreferences

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.66

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

immunolocalization

Stage

Tissue/Position (including subcellular localization)

Reference

oogenesis stage S7 -- S8 & adult stage | female

follicle cell

(Lerner et al., 2013)

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult head

• membrane

(Aradska et al., 2015)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

located_in endomembrane system

inferred from high throughput direct assay

(Tan et al., 2009)

located_in endoplasmic reticulum exit site

inferred from direct assay

(Lerner et al., 2013, Wendler et al., 2010)

located_in Golgi apparatus

inferred from direct assay

(Bard et al., 2006)

located_in Golgi cis cisterna

inferred from direct assay

(Lerner et al., 2013)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Tango1 in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\Tango1

View exonic expression by tissue for Dmel\Tango1

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

33930/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0286898

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0031842

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0286898

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 7 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 17 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Tango1

Transgenic constructs containing regulatory region of Tango1

Aberrations (Deficiencies and Duplications) ( 1 )

Inferred from experimentation ( 1 )

Gene disrupted in

Df(2L)BSC187

(Ríos-Barrera et al., 2017)

Inferred from location ( 0 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal, with Scer\GAL4^GMR.PFa

Tango1^HMS05801

lethal, with Scer\GAL4^sr-md710

Tango1^GD956

lethal (with Tango1^GS15095)

Tango1^GS17108

lethal (with Tango1^GS17108)

Tango1^GS15095

lethal | recessive

Tango1^2L3443

lethal - all die before end of larval stage

Tango1^2L3443

lethal - all die before end of pupal stage, with Scer\GAL4^pnr-MD237

Tango1^GD956

lethal - all die during first instar larval stage

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

Tango1^GD956

viable, with Scer\GAL4^Mef2.PR

Tango1^GD956

viable, with Scer\GAL4^tin.CΔ4

Tango1^GD956

viable (with Df(2L)BSC187)

Tango1^k14206

Other Phenotypes

Allele

decreased size | larval stage, with Scer\GAL4^sr-md710

Tango1^GD956

decreased size | P-stage, with Scer\GAL4^sr-md710

Tango1^GD956

long lived | RU486 conditional, with Scer\GAL4^{elav.Switch.PO}

Tango1^HMS05801

majority die during embryonic stage

Tango1^2L3443

short lived | heat sensitive, with Scer\GAL4^tin.CΔ4

Tango1^GD956

some die during larval stage

Tango1^2L3443

some die during pupal stage, with Scer\GAL4^pnr-MD237

Tango1^GD956

Phenotype manifest in

Allele

dorsal longitudinal indirect flight muscle | P-stage, with Scer\GAL4^sr-md710

Tango1^GD956

embryonic/larval fat body | third instar larval stage, with Scer\GAL4^{SPARC-MI00329-GAL4}

Tango1^GD956

embryonic/larval proventriculus outer layer, with Scer\GAL4^unspecified

Tango1^GD956

embryonic/larval tendon cell | larval stage, with Scer\GAL4^sr-md710

Tango1^GD956

embryonic/larval tracheal system | somatic clone

Tango1^2L3443

endoplasmic reticulum exit site, with Scer\GAL4^bs.Term

Tango1^NIG.11098R

endoplasmic reticulum exit site | larval stage, with Scer\GAL4^apolpp.PB

Tango1^NIG.11098R

endoplasmic reticulum exit site | larval stage, with Scer\GAL4^nub.PK

Tango1^NIG.11098R

endoplasmic reticulum exit site | larval stage, with Scer\GAL4^ptc.PU

Tango1^NIG.11098R

endoplasmic reticulum exit site | somatic clone

Tango1^2L3443

extracellular matrix | third instar larval stage, with Scer\GAL4^{SPARC-MI00329-GAL4}

Tango1^GD956

fat body, with Scer\GAL4^apolpp.PB

Tango1^NIG.11098R

fat cell | third instar larval stage, with Scer\GAL4^{SPARC-MI00329-GAL4}

Tango1^GD956

Golgi apparatus, with Scer\GAL4^bs.Term

Tango1^NIG.11098R

larva, with Scer\GAL4^sr-md710

Tango1^GD956

larval brain neuropil glial cell, with Scer\GAL4^repo.PU

Tango1^NIG.11098R

muscle tendon junction | P-stage, with Scer\GAL4^sr-md710

Tango1^GD956

secondary tracheal branch, with Scer\GAL4^bs.Term

Tango1^NIG.11098R

secondary tracheal branch | somatic clone

Tango1^2L3443

secretory granule, with Scer\GAL4^unspecified

Tango1^GD956

tendon cell | P-stage, with Scer\GAL4^sr-md710

Tango1^GD956

tendon cell | pupal stage, with Scer\GAL4^sr-md710

Tango1^NIG.11098R

terminal tracheal cell, with Scer\GAL4^bs.Term

Tango1^NIG.11098R

terminal tracheal cell | somatic clone

Tango1^2L3443

tracheal section, with Scer\GAL4^bs.Term

Tango1^NIG.11098R

tracheal section | somatic clone

Tango1^2L3443

wing pouch, with Scer\GAL4^nub.PK

Tango1^NIG.11098R

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (15)

Hsap\MIA2

6 of 14

Yes

Hsap\MIA3

6 of 14

Yes

Hsap\CTAGE1

4 of 14

Yes

Hsap\CTAGE4

4 of 14

Yes

Hsap\CTAGE6

4 of 14

Yes

Hsap\CTAGE8

4 of 14

Yes

Hsap\CTAGE9

4 of 14

Yes

Hsap\CTAGE15

4 of 14

Yes

Hsap\MIA

2 of 14

Yes

Hsap\OTOR

2 of 14

Yes

Hsap\AHI1

1 of 14

Hsap\CTAGE3P

1 of 14

Yes

Hsap\SPZ1

1 of 14

Yes

Hsap\VAV2

1 of 14

Hsap\VAV3

1 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (7)

Rnor\Mia2

5 of 14

Yes

Rnor\Mia3

4 of 14

Yes

Rnor\Mia

2 of 14

Yes

Rnor\Otor

2 of 14

Yes

Rnor\Spz1

1 of 14

Yes

Rnor\Vav2

1 of 14

Rnor\Vav3

1 of 14

Mus musculus (laboratory mouse) (7)

Mmus\Mia2

6 of 14

Yes

Mmus\Mia3

6 of 14

Yes

Mmus\Mia

2 of 14

Yes

Mmus\Otor

2 of 14

Yes

Mmus\Spz1

1 of 14

Yes

Mmus\Vav2

1 of 14

Mmus\Vav3

1 of 14

Xenopus tropicalis (Western clawed frog) (5)

Xtro\mia2

3 of 13

Yes

Xtro\mia3

3 of 13

Yes

Xtro\LOC100496268

2 of 13

Xtro\cnih4

1 of 13

Xtro\otor

1 of 13

Yes

Danio rerio (Zebrafish) (7)

Drer\mia3

7 of 14

Yes

Drer\mia2

4 of 14

Yes

Drer\mia

2 of 14

Yes

Drer\ctage5

1 of 14

Yes

Drer\myh14

1 of 14

Drer\myo18ab

1 of 14

Drer\vav2

1 of 14

Caenorhabditis elegans (Nematode, roundworm) (0)

Anopheles gambiae (African malaria mosquito) (2)

Agam\AgaP_AGAP007919

9 of 12

Yes

Agam\AgaP_AGAP003445

1 of 12

Arabidopsis thaliana (thale-cress) (0)

Saccharomyces cerevisiae (Brewer's yeast) (0)

Schizosaccharomyces pombe (Fission yeast) (0)

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:Tango1. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (1)

CG11368

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Allele

Disease

Interaction

References

Tango1^HMS05801

exacerbates cancer

modeled by Rbf^HMS03004

(Parkhitko et al., 2021)

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

MIA2; MIA SH3 domain ER export factor 2

6 of 14

602132

MIA3; MIA SH3 domain ER export factor 3

6 of 14

613455

ODONTOCHONDRODYSPLASIA 2 WITH HEARING LOSS AND DIABETES; ODCD2

CTAGE1; cutaneous T cell lymphoma-associated antigen 1

4 of 14

608856

CTAGE4; CTAGE family member 4

4 of 14

608910

CTAGE6; CTAGE family member 6

4 of 14

CTAGE8; CTAGE family member 8

4 of 14

CTAGE9; CTAGE family member 9

4 of 14

CTAGE15; CTAGE family member 15

4 of 14

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Show neighbor-neighbor interactions:

Off

Show/hide secondary interactors
(data from AllianceMine provided by esyN)

Select Layout:

Force Directed

Circle

Concentric

Legend:

Protein

RNA

Selected Interactor(s)

Interactions Browser

View in Interactions Browser

Please see the Physical Interaction reports below for full details

MIST Molecular Interaction Search Tool

View in MIST tool (external link)

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

Tango1

anti tag coimmunoprecipitation, anti tag western blot

(Reynolds et al., 2019, Liu et al., 2017)

Tango1 - GM130

anti tag coimmunoprecipitation, western blot

(Liu et al., 2017)

Tango1 - Grasp65

anti tag coimmunoprecipitation, western blot

(Liu et al., 2017)

Tango1 - Rab1

anti tag coimmunoprecipitation, western blot

(Liu et al., 2017)

Tango1 - Sar1

anti tag coimmunoprecipitation, western blot

(Liu et al., 2017)

Summary of Genetic Interactions

esyN Network Diagram

Show/hide secondary interactors
(data from AllianceMine provided by esyN)

esyN Network Key:

Suppression

Enhancement

View in Interactions Browser View in MIST tool (external link)

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Tango1

suppressible

dpy

(Ríos-Barrera et al., 2017)

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Pgant4

suppressible

Tango1

(Zhang et al., 2014)

External Data

Linkouts

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

External Data

Linkouts

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

2-21

Cytogenetic map

26F3-26F5

Sequence location

2L:6,649,388..6,654,574 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

26F3-26F5

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

2-21

(FlyBase, 2016)

2-21.5

(Comeron et al., 2012)

(Baer et al., 2007)

Left of (cM)

Right of (cM)

Notes

Maps to 2L.

(Baer et al., 2007)

Stocks and Reagents

Stocks (14)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

11121

y¹ w^67c23; P{lacW}Tango1^k14206/CyO

77171

y¹ sc^* v¹ sev²¹; P{TRiP.HMS05964}attP2

600027

y¹ w^*; TI{CRIMIC.TG4.1}Tango1^{CR70962-TG4.1}/SM6a

67886

y¹ sc^* v¹ sev²¹; P{TRiP.HMS05801}attP40

67887

y¹ sc^* v¹ sev²¹; P{TRiP.HMS05802}attP40

Kyoto

203074

y¹ w^67c23; P{GSV7}Tango1^GS21664/SM1

206078

y¹ w^67c23; P{GSV6}Tango1^GS15095/SM1

206906

y¹ w^67c23; P{GSV6}Tango1^GS17108/SM1

NIG-Fly

M2L-2694

y¹ w¹¹¹⁸; Tango1^SK1 P{neoFRT}40A/CyO-Tb

VDRC

v330015

P{VSH330015}attP40

v21594

w¹¹¹⁸; P{GD956}v21594/TM3

v318173

PBac{fTRG00602.sfGFP-TVPTBF}VK00033

More stocks available...

Genomic Clones (22)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (23)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

Antibody Information

Laboratory Generated Antibodies

polyclonal

(Zhang et al., 2014, Lerner et al., 2013)

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

dsRNA directed against this gene has been used in a screen for genes required for constitutive protein secretion.

(Bard et al., 2006)

dsRNA directed against Tango1 inhibits protein secretion in S2 cells and results in fusion of Golgi membranes with the endoplasmic reticulum in more than 50% of the treated cells.

(Bard et al., 2006)

Relationship to Other Genes

Source for database merge of

Source for merge of: Tango1 2L3443

(Ríos-Barrera et al., 2017)

Additional comments

Nomenclature History

Source for database identify of

Source for identity of: Tango1 CG11098

(Bard et al., 2006)

Nomenclature comments

Etymology

Synonyms and Secondary IDs (7)

Reported As

Symbol Synonym

2L3443

CG11098

(National Institute of Genetics Fly Stocks, 2022-, Kim et al., 2021, Meadows, 2017.1.11, Hosono et al., 2015, Jaspers et al., 2012, Wendler et al., 2010, Perkins et al., 2009, Andersen and Tapon, 2008, Bard et al., 2006, Milchanowski et al., 2004)

TANGO1

(Wakana et al., 2013, Wendler et al., 2010, Bard et al., 2006)

tango1

(Zhang et al., 2017, Tiwari et al., 2015)

Name Synonyms

Transport and Golgi organization 1

(Tiwari et al., 2015, Jaspers et al., 2012, Bard et al., 2006)

transport and Golgi organisation 1

(Wendler et al., 2010)

Secondary FlyBase IDs

FBgn0031842
FBgn0260099

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 36 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

33930

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q9VMA7

UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information

Q9VMA7

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

X2J786

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q9VMA7

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

33930/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0286898

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0286898

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG11098

MARRVEL_MODEL - MARRVEL (model organism gene)

33930

Linkouts

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0031842

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0286898

Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution

Interactive Fly

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

References (64)

The following external sites may use different assemblies or annotations than FlyBase.

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