FlyBase Allele Report: Scer\GAL4[c768]

General Information

Symbol

Scer\GAL4^c768

Species

S. cerevisiae

Name

FlyBase ID

FBal0063261

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

P{GawB}Meltrin^c768

Carried in Construct

Also Known As

c768-Gal4, c768

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Manseau et al., 1997)

Progenitor genotype

Associated Insertion(s)

P{GawB}Meltrin^c768

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{GawB}

enhancer trap

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3R:14,641,175..14,741,174

(Zhou et al., 2019, Chen et al., 2014, Lee and Spradling, 2014, Wang et al., 2011, Skora and Spradling, 2010, Gilbert et al., 2006, Morris et al., 2006, Manseau et al., 1997)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 16

embryonic/larval central nervous system

(Manseau et al., 1997)

embryonic/larval brain

(Manseau et al., 1997)

first instar larval stage -- third instar larval stage

optic lobe neuroepithelial cell of larval optic anlage

(Chen et al., 2014)

second instar larval stage -- third instar larval stage

optic lobe neuroepithelial cell of larval outer optic anlage

(Wang et al., 2011)

embryonic/larval brain | restricted

(Wang et al., 2011)

larval ventral nerve cord | restricted

(Wang et al., 2011)

third instar larval stage

wing pouch

(Bloomington Drosophila Stock Center, 2017)

wandering third instar larval stage

larval inner optic anlage

(Manseau et al., 1997)

haltere disc | restricted

(Manseau et al., 1997)

larval ventral nerve cord

(Manseau et al., 1997)

wing disc | restricted

(Manseau et al., 1997)

larval outer optic anlage

(Manseau et al., 1997)

adult stage oogenesis stage S9 -- S14

follicle cell | posterior

(Manseau et al., 1997)

Additional Information

Statement

Reference

ScerGAL4^C855a drives expression from the end of the first instar onwards in the neuroepithelial cells of the outer optic anlage (OPC), as well as in some cells in the central brain and the ventral nerve cord.

(Wang et al., 2011)

In third instar larva, expression in wing and haltere discs most pronounced in pouch region. In ovary expressed in all follicle cells overlying oocyte, starting at stage S9.

(Manseau et al., 1997)

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal mitotic cell cycle | third instar larval stage, with Cdk1^GD10728

(Zhou and Luo, 2013)

abnormal mitotic cell cycle | third instar larval stage, with Cdk1^JF03004

(Zhou and Luo, 2013)

abnormal mitotic cell cycle | third instar larval stage, with CycB^HMS01015

(Zhou and Luo, 2013)

abnormal mitotic cell cycle | third instar larval stage, with CycE^KK102511

(Zhou and Luo, 2013)

abnormal mitotic cell cycle | third instar larval stage, with E2f1^KK100304

(Zhou and Luo, 2013)

abnormal neuroanatomy | larval stage, with N^NIG.3936R

(Wang et al., 2011)

abnormal neuroanatomy | larval stage, with RPA1^GD4228

(Zhou and Luo, 2013)

abnormal neuroanatomy | larval stage, with RPA2^GD4430

(Zhou and Luo, 2013)

abnormal neuroanatomy | larval stage, with RPA3^GD4799

(Zhou and Luo, 2013)

abnormal neuroanatomy | third instar larval stage, with Treh^GD5118

(Chen et al., 2014)

decreased cell number | third instar larval stage, with Delta^UAS.cUa

(Wang et al., 2011)

lethal, with Delta::N^ΔECN.UAS

(Wang et al., 2011)

Phenotype Manifest In

embryonic/larval optic lobe | temperature conditional, with Delta::N^ΔECN.UAS, Scer\GAL80^ts.αTub84B

(Wang et al., 2011)

lamina | third instar larval stage, with Treh^GD5118

(Chen et al., 2014)

lamina anlage, with N^NIG.3936R

(Wang et al., 2011)

lamina anlage, with RPA1^GD4228

(Zhou and Luo, 2013)

lamina anlage, with RPA2^GD4430

(Zhou and Luo, 2013)

lamina anlage, with RPA3^GD4799

(Zhou and Luo, 2013)

larval optic anlage, with numb^{RNAi.UAS.THU1674}

(Zhou and Luo, 2013)

larval optic anlage, with RPA1^GD4228

(Zhou and Luo, 2013)

larval optic anlage, with RPA2^GD4430

(Zhou and Luo, 2013)

larval optic anlage, with Stat92E^{ΔNΔC.UASp.Tag:HA}

(Zhou and Luo, 2013)

larval optic anlage, with yki^{S168A.UAS.Tag:V5}

(Zhou and Luo, 2013)

larval outer optic anlage, with Cdk1^GD10728

(Zhou and Luo, 2013)

larval outer optic anlage, with Cdk1^JF03004

(Zhou and Luo, 2013)

larval outer optic anlage, with Cdk2^KK112530

(Zhou and Luo, 2013)

larval outer optic anlage, with CycA^JF02472

(Zhou and Luo, 2013)

larval outer optic anlage, with CycA^KK101548

(Zhou and Luo, 2013)

larval outer optic anlage, with CycB^HMS01015

(Zhou and Luo, 2013)

larval outer optic anlage, with CycE^JF02473

(Zhou and Luo, 2013)

larval outer optic anlage, with CycE^KK102511

(Zhou and Luo, 2013)

larval outer optic anlage, with Delta^UAS.cUa

(Wang et al., 2011)

larval outer optic anlage, with E2f1^KK100304

(Zhou and Luo, 2013)

larval outer optic anlage, with N^NIG.3936R

(Wang et al., 2011)

larval outer optic anlage, with PCNA^GD4205

(Zhou and Luo, 2013)

larval outer optic anlage, with RPA3^GD4799

(Zhou and Luo, 2013)

larval outer optic anlage | third instar larval stage, with Treh^GD5118

(Chen et al., 2014)

medulla anlage, with Delta^UAS.cUa

(Wang et al., 2011)

medulla anlage, with N^NIG.3936R

(Wang et al., 2011)

medulla anlage, with RPA1^GD4228

(Zhou and Luo, 2013)

medulla anlage, with RPA2^GD4430

(Zhou and Luo, 2013)

medulla anlage, with RPA3^GD4799

(Zhou and Luo, 2013)

medulla anlage | temperature conditional, with Delta::N^ΔECN.UAS, Scer\GAL80^ts.αTub84B

(Wang et al., 2011)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressed by

Statement

Reference

RPA3^GD4799, Scer\GAL4^c768 has larval optic anlage phenotype, suppressible by N^UAS.cSb, Scer\GAL4^c768

(Zhou and Luo, 2013)

RPA3^GD4799, Scer\GAL4^c768 has larval optic anlage phenotype, suppressible by numb^{RNAi.UAS.THU1674}, Scer\GAL4^c768

(Zhou and Luo, 2013)

RPA3^GD4799, Scer\GAL4^c768 has larval optic anlage phenotype, suppressible by yki^{S168A.UAS.Tag:V5}, Scer\GAL4^c768

(Zhou and Luo, 2013)

NOT suppressed by

Statement

Reference

RPA3^GD4799, Scer\GAL4^c768 has larval optic anlage phenotype, non-suppressible by Stat92E^{ΔNΔC.UASp.Tag:HA}, Scer\GAL4^c768

(Zhou and Luo, 2013)

Suppressor of

Statement

Reference

N^UAS.cSb, Scer\GAL4^c768 is a suppressor of larval optic anlage phenotype of RPA3^GD4799, Scer\GAL4^c768

(Zhou and Luo, 2013)

numb^{RNAi.UAS.THU1674}, Scer\GAL4^c768 is a suppressor of larval optic anlage phenotype of RPA3^GD4799, Scer\GAL4^c768

(Zhou and Luo, 2013)

yki^{S168A.UAS.Tag:V5}, Scer\GAL4^c768 is a suppressor of larval optic anlage phenotype of RPA3^GD4799, Scer\GAL4^c768

(Zhou and Luo, 2013)

NOT Suppressor of

Statement

Reference

Stat92E^{ΔNΔC.UASp.Tag:HA}, Scer\GAL4^c768 is a non-suppressor of larval optic anlage phenotype of RPA3^GD4799, Scer\GAL4^c768

(Zhou and Luo, 2013)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

3742

w¹¹¹⁸; P{GawB}Meltrin^c768/TM3, Sb¹

Kyoto

107214

w¹¹¹⁸; P{GawB}Meltrin^c768/TM3, Sb¹ Ser¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

GAL4^c768

Scer\GAL4^c768

Name Synonyms

Secondary FlyBase IDs

References (10)

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