FB2024_03 , released June 25, 2024
Allele: Dmel\tkvUAS.cLa
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General Information
Symbol
Dmel\tkvUAS.cLa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Lecuit
FlyBase ID
FBal0094313
Feature type
allele
Associated gene
Dmel\tkv
Associated Insertion(s)
Carried in Construct
P{UAS-tkv.La}
Also Known As
UAS-tkv
Key Links
Transgenic product class
wild_type
(Lecuit and Cohen, 1998)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Lecuit and Cohen, 1998)
Mutagen
in vitro construct
(Lecuit and Cohen, 1998)
Progenitor genotype
Carried in construct
P{UAS-tkv.La}
Cytology
Description

Expression of tkv coding region is governed by UASt regulatory sequences.

(Lecuit and Cohen, 1998)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
tkv
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of tkvScer\UAS.cLa under the control of Scer\GAL4dpp.blk1 results in flies with smaller wings than normal.

      (de Navas et al., 2006)

      When expression is driven by Scer\GAL471B, the wing is reduced in size. The effect is stronger in the posterior compartment, with the region between veins 4 and 5 being more reduced than the region between veins 2 and 3. The region between veins 3 and 4 is relatively normal.

      (Lecuit and Cohen, 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The increased size of the posterior compartment that is seen in the haltere discs of Ubx6.28/Ubxpbx-1 animals is partially suppressed by expression of tkvScer\UAS.cLa under the control of Scer\GAL4en-e16E.

      The increased size of the anterior compartment that is seen in the haltere discs of Ubx6.28/Ubxbx-3 animals is partially suppressed by expression of tkvScer\UAS.cLa under the control of Scer\GAL4ptc-559.1.

      (de Navas et al., 2006)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      tkvScer\UAS.cLa
      tkvUAS.cLa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Lecuit
      (Lecuit and Cohen, 1998)
      Secondary FlyBase IDs
        References (4)