FB2024_03 , released June 25, 2024
Allele: Dmel\grkUAS.cGa
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General Information
Symbol
Dmel\grkUAS.cGa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Ghiglione
FlyBase ID
FBal0135712
Feature type
allele
Associated gene
Dmel\grk
Associated Insertion(s)
Carried in Construct
P{UAS-grk.G}
Key Links
Transgenic product class
wild_type
(Ghiglione et al., 2002)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Ghiglione et al., 2002)
Mutagen
in vitro construct
(Ghiglione et al., 2002)
Progenitor genotype
Carried in construct
P{UAS-grk.G}
Cytology
Description

UAS regulatory sequences drive expression of wild-type grk.

(Ghiglione et al., 2002)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
grk
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of grkScer\UAS.cGa in the follicle cells under the control of Scer\GAL4CY2 results in a weakly dorsalised egg shell (dorsal appendages are thickened) in 78% of cases. The resulting embryos are also dorsalised. Expression of grkScer\UAS.cGa under the control of Scer\GAL4Bx-MS1096 results in ectopic wing veins in the wing.

      (Ghiglione et al., 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Phenotype Manifest In
      Enhanced by
      Suppressed by
      Statement
      Reference

      Scer\GAL4CY2, grkUAS.cGa has egg chorion phenotype, suppressible by Sunspecified/S[+]

      (Ghiglione et al., 2002)

      Scer\GAL4CY2, grkUAS.cGa has dorsal appendage phenotype, suppressible by Sunspecified/S[+]

      (Ghiglione et al., 2002)
      Enhancer of
      Statement
      Reference

      Scer\GAL4CY2/grkUAS.cGa is an enhancer of egg chorion phenotype of Scer\GAL4CY2, stetUAS.cGa

      (Ghiglione et al., 2002)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of SScer\UAS.cBa and grkScer\UAS.cGa in the follicle cells under the control of Scer\GAL4CY2 results in strong dorsalisation of the eggshell. Co-expression of stetScer\UAS.cGa and grkScer\UAS.cGa in the follicle cells under the control of Scer\GAL4CY2 results in strong dorsalisation of the eggshell.

      (Ghiglione et al., 2002)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      grkScer\UAS.cGa
      grkUAS.cGa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Ghiglione
      (Ghiglione et al., 2002)
      Secondary FlyBase IDs
        References (1)