FB2024_03 , released June 25, 2024
Allele: Dmel\dxΔPRM.UAS
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General Information
Symbol
Dmel\dxΔPRM.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0138238
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

UASt sequences drive expression of dx which has had amino acids 475 to 483, a proline rich motif, removed.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of dxΔPRM.Scer\UAS under the control of Scer\GAL4ap-md544 results in ectopic joints in the leg.

When dxΔNBS.Scer\UAS is driven by Scer\GAL4ptc-559.1, wing nicking is seen.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
NOT Suppressor of
Statement
Reference

Scer\GAL4ap-md544/dxΔPRM.UAS is a non-suppressor of visible phenotype of dsh1

Phenotype Manifest In
NOT Suppressor of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

Expression of dxΔPRM.Scer\UAS under the control of Scer\GAL4ap-md544 has no effect on the ectopic leg joint phenotype of dsh1 flies.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

The combination of dxΔPRM.Scer\UAS and dxScer\UAS.cMa (driven by Scer\GAL4ptc-559.1) suppresses the phenotypes seen with either construct alone.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
dxΔPRM.Scer\UAS
dxΔPRM.UAS
Name Synonyms
Secondary FlyBase IDs
    References (3)