FlyBase Allele Report: Dmel\bs[UAS.cHa]

General Information

Symbol

Dmel\bs^UAS.cHa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Han

FlyBase ID

FBal0180653

Feature type

allele

Associated gene

Dmel\bs

Associated Insertion(s)

Carried in Construct

P{UAS-bs.H}

Also Known As

UAS-DSRF, UAS-bs

Key Links

Transgenic product class

wild_type

(Han et al., 2004)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Han et al., 2004)

Mutagen

in vitro construct

(Han et al., 2004)

Progenitor genotype

Carried in construct

P{UAS-bs.H}

Cytology

Description

UAS regulatory sequences drive expression of bs.

(Han et al., 2004)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal courtship behavior, with Scer\GAL80^cry.PS

(Donlea et al., 2009)

abnormal locomotor behavior | adult stage, with Scer\GAL4^ftz.ng

(Thran et al., 2013)

abnormal size | adult stage, with Scer\GAL4^Bx-MS1096

(Han et al., 2004)

visible, with Scer\GAL4^Bx-MS1096

(Han et al., 2004)

Phenotype Manifest In

wing cell, with Scer\GAL4^Bx-MS1096

(Han et al., 2004)

wing vein, with Scer\GAL4^Bx-MS1096

(Han et al., 2004)

Detailed Description

Statement

Reference

Expressing bs^Scer\UAS.cHa under the control of Scer\GAL4^ftz.ng (R4) leads to general locomotor and orientation defects.

(Thran et al., 2013)

Repression of bs^Scer\UAS.cHa expression by Scer\GAL80^cry.PS results in significant courtship suppression.

(Donlea et al., 2009)

Expression of bs^Scer\UAS.cHa under the control of Scer\GAL4^Bx-MS1096 results in a reduction of veins and overproliferation of intervein tissues in the wing.

(Han et al., 2004)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^Bx-MS1096, bs^UAS.cHa has abnormal size | adult stage phenotype, enhanceable by Mrtf^UAS.cHa, Scer\GAL4^Bx-MS1096

(Han et al., 2004)

Enhancer of

Statement

Reference

bs^UAS.cHa, Scer\GAL4^Bx-MS1096 is an enhancer of abnormal size | adult stage phenotype of Mrtf^UAS.cHa, Scer\GAL4^Bx-MS1096

(Han et al., 2004)

Suppressor of

Statement

Reference

bs^UAS.cHa, Scer\GAL4^ptc-559.1 is a suppressor of visible phenotype of Atg1^UAS.cCa, Scer\GAL4^ptc-559.1

(Chen et al., 2008)

Phenotype Manifest In

Suppressor of

Statement

Reference

bs^UAS.cHa, Scer\GAL4^ptc-559.1 is a suppressor of anterior crossvein phenotype of Atg1^UAS.cCa, Scer\GAL4^ptc-559.1

(Chen et al., 2008)

bs^UAS.cHa, Scer\GAL4^ptc-559.1 is a suppressor of wing hair phenotype of Atg1^UAS.cCa, Scer\GAL4^ptc-559.1

(Chen et al., 2008)

bs^UAS.cHa, Scer\GAL4^32B is a suppressor of wing phenotype of Pax^UAS.cCa, Scer\GAL4^32B

(Chen et al., 2005)

Additional Comments

Genetic Interactions

Statement

Reference

Overexpression of bs^Scer\UAS.cHa significantly suppresses the Scer\GAL4^ptc-559.1-driven Atg1^Scer\UAS.cCa-induced wing defects.

(Chen et al., 2008)

Expression of bs^Scer\UAS.cHa in flies expressing Pax^Scer\UAS.cCa under the control of Scer\GAL4^32B suppresses the blistered-wing phenotype.

(Chen et al., 2005)

Co-expression of bs^Scer\UAS.cHa and Mrtf^Scer\UAS.cHa under the control of Scer\GAL4^Bx-MS1096 enhances the reduction of veins and overproliferation of intervein tissues in the wing that is seen when either bs^Scer\UAS.cHa or Mrtf^Scer\UAS.cHa are expressed separately under the control of Scer\GAL4^Bx-MS1096.

(Han et al., 2004)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^c105/bs^UAS.cHa rescues bs²

(Thran et al., 2013)

Scer\GAL4^EB1/bs^UAS.cHa rescues bs²

(Thran et al., 2013)

Scer\GAL4^Alp4-c232/bs^UAS.cHa rescues bs²

(Thran et al., 2013)

bs^UAS.cHa/Scer\GAL4^bs-1348 rescues bs¹³⁴⁸

(Donlea et al., 2009)

Comments

Expression of bs^Scer\UAS.cHa in ring neurons under the control of any of Scer\GAL4^c105 (R1), Scer\GAL4^EB1 (R2) or Scer\GAL4^Aph-4-c232 (R3/R4d) rescues the visual orientation memory defects seen in heterozygous bs² mutants. Expressing bs^Scer\UAS.cHa under the control of Scer\GAL4^ftz.ng (R4) in bs² mutant flies leads to general locomotor and orientation defects so these flies could not be tested for visual orientation memory phenotype defects.

(Thran et al., 2013)

Expression of bs^Scer\UAS.cHa in bs¹³⁴⁸ mutants under the control of Scer\GAL4^bs-1348 rescues experience-dependent increases in sleep.

Expression of bs^Scer\UAS.cHa in bs¹³⁴⁸ mutants under the control of Scer\GAL4^bs-1348 rescues long-term memory.

Repression of bs^Scer\UAS.cHa expression (under the control of Scer\GAL4^bs-1348) by Scer\GAL80^cry.PS in lateral neurons results in a loss of long-term memory. The morphology of LN[v]]s in bs¹³⁴⁸/+ flies does not differ from that of LN[[v]]s in mutant Scer\GAL4^bs-1348/bs^Scer\UAS.cHa flies.

(Donlea et al., 2009)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

bs^Scer\UAS.cHa

bs^UAS.cHa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Han

(Han et al., 2004)

Secondary FlyBase IDs

References (7)

Report Sections

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