FB2024_03 , released June 25, 2024
Allele: Dmel\forUAS.cWa
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General Information
Symbol
Dmel\forUAS.cWa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Wang
FlyBase ID
FBal0246710
Feature type
allele
Associated gene
Dmel\for
Associated Insertion(s)
Carried in Construct
P{UAS-for.P1.W}
Also Known As
UAS-forP1
Key Links
Transgenic product class
wild_type
(Wang et al., 2008)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Wang et al., 2008)
Mutagen
in vitro construct
(Wang et al., 2008)
Progenitor genotype
Carried in construct
P{UAS-for.P1.W}
Cytology
Description

UASt regulatory sequences drive expression of the P1 isoform of for.

(Wang et al., 2008)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
for
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Overexpression of forScer\UAS.cWa driven by Scer\GAL4c819 does not boost memory.

      (Wang et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      forUAS.cWa, Scer\GAL4elav.PU is a suppressor of abnormal memory phenotype of FdhUAS.cHa, Scer\GAL4elav.PU

      (Hou et al., 2011)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Scer\GAL4elav.PU-driven expression of forScer\UAS.cWa pan-neuronally suppresses the defects in visual pattern memory found upon expression of FdhScer\UAS.cHa neuronally (also under the control of Scer\GAL4elav.PU).

      (Hou et al., 2011)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      forUAS.cWa/Scer\GAL4elav.PLu rescues fors

      (Wang et al., 2008)

      forUAS.cWa/Scer\GAL4c819 rescues fors

      (Wang et al., 2008)

      forUAS.cWa, Scer\GAL4c819, Scer\GAL80ts.αTub84B rescues fors

      (Wang et al., 2008)
      Partially rescues

      forUAS.cWa/Scer\GAL4NP6561 partially rescues fors

      (Li et al., 2009)

      forUAS.cWa/Scer\GAL4c205 partially rescues fors

      (Wang et al., 2008)

      forUAS.cWa, Scer\GAL4c205, Scer\GAL80ts.αTub84B partially rescues fors

      (Wang et al., 2008)

      forUAS.cWa/Scer\GAL4cv-c-C5 partially rescues fors

      (Wang et al., 2008)
      Fails to rescue

      forUAS.cWa/Scer\GAL4Mef2.247.Switch fails to rescue fors

      (Wang et al., 2008)

      forUAS.cWa/Scer\GAL4Alp4-c232 fails to rescue fors

      (Wang et al., 2008)
      Comments

      Expression of forScer\UAS.cWa driven by Scer\GAL4NP6561 rescues the memory defect for "contour orientation" of homozygous fors flies.

      Expression of forScer\UAS.cWa driven by Scer\GAL4NP6561 fails to rescue the memory defect for "elevation" of homozygous fors flies.

      (Li et al., 2009)

      Pan-neural expression of forScer\UAS.cWa via Scer\GAL4elav.PLu rescues the memory defect in fors mutants.

      Expression of forScer\UAS.cWa via Scer\GAL4c205 is sufficient to partially restore visual pattern memory in fors flies. Only memory for "elevation" is restored, but not that for "contour".

      Temperature shift experiments using Scer\GAL80ts.αTub84B demonstrate that Scer\GAL4c205-driven forScer\UAS.cWa expression in adults is sufficient for the rescue of the fors visual memory defects.

      Expression of forScer\UAS.cWa via Scer\GAL4c819 is sufficient to restore visual pattern memory in fors flies. Memory for both "elevation" and "contour" is restored.

      Temperature shift experiments using Scer\GAL80ts.αTub84B demonstrate that Scer\GAL4c819-driven forScer\UAS.cWa expression in adults is sufficient for the rescue of the fors visual memory defects.

      Expression of forScer\UAS.cWa driven by Scer\GAL4Mef2.247.Switch fails to rescue the memory defects of fors mutants.

      Expression of forScer\UAS.cWa driven by Scer\GAL4C5 rescues only the defect in memory for "elevation", but not the defect in memory for "contour orientation".

      Expression of forScer\UAS.cWb via Scer\GAL4Aph-4-c232 is not sufficient to restore visual pattern memory in fors flies.

      (Wang et al., 2008)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      forScer\UAS.cWa
      forUAS.cWa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Wang
      Secondary FlyBase IDs
        References (3)