FB2024_03 , released June 25, 2024
Allele: Dmel\mTorHMS01114
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General Information
Symbol
Dmel\mTorHMS01114
Species
D. melanogaster
Name
FlyBase ID
FBal0257777
Feature type
allele
Associated gene
Dmel\mTor
Associated Insertion(s)
Carried in Construct
P{TRiP.HMS01114}
Also Known As
UAS-Tor-RNAi, Tor RNAi, TorHMS01114, UAS-Tor RNAi
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Ni et al., 2010.12.1)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Ni et al., 2010.12.1)
Mutagen
in vitro construct
(Ni et al., 2010.12.1)
Progenitor genotype
Carried in construct
P{TRiP.HMS01114}
Cytology
Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
dsRNA-HMS01114
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression under the control of Scer\GAL4eya.enh1+E+2 results in rough, necrotic and small eye phenotype.

      (Pletcher et al., 2019)

      The expression of TorHMS01114 under the control of Scer\GAL4nos.PG leads to germline degeneration in the germarium.

      (Wang et al., 2019)

      Scer\GAL4bs.PM-mediated expression of TorHMS01114 results in decreased terminal cell branching and induction of long, branched autocellular, seamed tubes extend well beyond the terminal cell nucleus.

      (Francis and Ghabrial, 2015)

      Scer\GAL4Ilp2.PR-mediated expression results in a significant reduction in the body weight of emerging adults compared to controls.

      (Hasygar and Hietakangas, 2014)

      Expression of TorHMS01114 under the control of either Scer\GAL4esg-NP5130 results in impaired intestinal stem cell proliferation in response to paraquat.

      (Tang et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      TorHMS01114
      (Kim et al., 2019, Francis and Ghabrial, 2015)
      mTorHMS01114
      Name Synonyms
      Secondary FlyBase IDs
        References (24)