FB2024_03 , released June 25, 2024
Allele: Dmel\obst-ECPTI002377
Open Close
General Information
Symbol
Dmel\obst-ECPTI002377
Species
D. melanogaster
Name
FlyBase ID
FBal0261842
Feature type
allele
Associated gene
Dmel\obst-E
Associated Insertion(s)
PBac{544.SVS-1}obst-ECPTI002377
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
piggyBac activity
(FlyProt project., 2011.8.8)
Progenitor genotype
Associated Insertion(s)
PBac{544.SVS-1}obst-ECPTI002377
Cytology
Description

Protein trap insertion line, in-frame.

(FlyProt project., 2011.8.8)
Allele components
Component
Use(s)
Inserted element
PBac{544.SVS-1}
Tagged with
Tag:StrepII
Venus
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      obst-ECPTI002377 homozygous pupae obst-ECPTI002377/obst-EKO as well as obst-ECPTI002377/obst-EDel transheterozygous pupae are longer and thinner than wild-type and have significantly higher axis ratio (AR, length/width), despite having normal appearance and AR in the larval stages.

      (Tajiri et al., 2017)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      obst-EDel/obst-ECPTI002377 is rescued by Scer\GAL4Act5C.PU/obst-EUAS.a

      (Tajiri et al., 2017)
      Partially rescued by

      obst-EDel/obst-ECPTI002377 is partially rescued by Scer\GAL4Act5C.PU/obst-Ea.EGFP

      (Tajiri et al., 2017)
      Not rescued by

      obst-EDel/obst-ECPTI002377 is not rescued by Scer\GAL4Act5C.PU/obst-EUAS.b

      (Tajiri et al., 2017)
      Comments

      The pupal shape defects (pupae are longer and thinner compared to wild-type and have higher axis ratio) characteristic for obst-ECPTI002377/obst-EDel transheterozygotes is rescued by expression of obst-EScer\UAS.a under the control of Scer\GAL4Act5C.PU in the mutant background.

      (Tajiri et al., 2017)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      obst-ECPTI002377
      (Tajiri et al., 2017)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)